Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | PDE9A | O76083 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.34 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523899 | 0.91 | CYP11B1 (0.40) | ARMAOAMAOBALDH1A1HPGD | |
| SCHEMBL24524254 | 0.85 | AR (0.39) | ARALDH1A1CA1CA2KDM4E | |
| SCHEMBL24523886 | 0.77 | ALDH1A1 (0.38) | MAOAMAOBALDH1A1HPGDMAPK1 | |
| SCHEMBL24524261 | 0.74 | PNMT (0.41) | ARALDH1A1CA1CA2KDM4E | |
| SCHEMBL24523891 | 0.74 | ALDH1A1 (0.39) | ARALDH1A1CA1CA2KDM4E | |
| SCHEMBL18411452 | 0.73 | TSHR (0.46) | ALDH1A1HPGDSMN1; SMN2LMNACA1 | |
| SCHEMBL24523907 | 0.73 | MAOA (0.40) | MAOAMAOBALDH1A1HPGDKDM4E | |
| SCHEMBL24523750 | 0.72 | MAOA (0.40) | MAOAMAOBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL28203556 | 0.72 | CA1 (0.47) | ARMAOAMAOBALDH1A1LMNA | |
| SCHEMBL24523848 | 0.71 | AR (0.33) | ARALDH1A1CA1CA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |