Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.32 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24523923 | 0.89 | RAB9A (0.34) | RAB9AEGLN1MAPTRXFP1ALDH1A1 | |
| SCHEMBL24524252 | 0.76 | IMPDH2 (0.37) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL19978063 | 0.75 | GPR3 (0.40) | RAB9AEGLN1MAPTRXFP1ALDH1A1 | |
| SCHEMBL24523766 | 0.74 | BRDT (0.36) | RAB9ASLC9A1SLC22A12GPR3 | |
| SCHEMBL24524251 | 0.73 | KDM4E (0.35) | RAB9AALDH1A1KDM4EMEN1HTT | |
| SCHEMBL16122442 | 0.73 | TNKS (0.36) | RAB9AEGLN1MAPTALDH1A1KDM4E | |
| SCHEMBL24523770 | 0.72 | IMPDH2 (0.38) | MAPTALDH1A1KDM4EMEN1HTT | |
| SCHEMBL21718193 | 0.72 | GPR3 (0.42) | RAB9AMAPTRXFP1ALDH1A1KDM4E | |
| SCHEMBL22450167 | 0.71 | DYRK1A (0.35) | RAB9AEGLN1MAPTALDH1A1KDM4E | |
| SCHEMBL24523731 | 0.71 | IMPDH2 (0.33) | MAPTALDH1A1KDM4EMEN1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |