SCHEMBL24523766

SCHEMBL24523766

N#Cc1cc2c(cc1-c1cccc3sc4ccccc4c13)c1cccc3c4cc(-c5cccc6sc7ccccc7c56)c(C#N)cc4n2c13

nearest known ligand 0.36

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRDT Q58F21 1/20 0.36
SLC22A12 Q96S37 1/20 0.34
RAB9A P51151 1/20 0.32
GPR3 P46089 1/20 0.31
SLC9A1 P19634 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24523763 0.79 MCL1 (0.43)
SCHEMBL24523762 0.79 KDM4E (0.33) RAB9A
SCHEMBL24523768 0.78 MAOA (0.38)
SCHEMBL24523775 0.76 KDM4E (0.39)
SCHEMBL21692687 0.76 GPR3 (0.38) BRDTSLC22A12GPR3SLC9A1
SCHEMBL24523907 0.76 MAOA (0.40)
SCHEMBL21692647 0.76 F9 (0.40) BRDTSLC22A12GPR3SLC9A1
SCHEMBL24523772 0.76 CA1 (0.36)
SCHEMBL24524245 0.75 TRPA1 (0.34) SLC22A12
SCHEMBL25567919 0.75 SLC9A1 (0.36) BRDTSLC22A12RAB9AGPR3SLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022129116-A1 INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS MERCK PATENT GMBH (DE) 2022-06-23 WO disclosed