Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 9/20 | 0.49 |
| ▸ | RARB | P10826 | 9/20 | 0.49 |
| ▸ | RARG | P13631 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | CASP1 | P29466 | 1/20 | 0.48 |
| ▸ | CASP7 | P55210 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP26A1 | O43174 | 2/20 | 0.41 |
| ▸ | CYP26B1 | Q9NR63 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29707990 | 0.81 | RXRA (0.44) | RARARARBRARGALDH1A1CYP3A4 | |
| SCHEMBL447737 | 0.81 | RXRA (0.44) | RARARARBRARGALDH1A1CYP3A4 | |
| SCHEMBL9054118 | 0.76 | RARB (0.47) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL8657926 | 0.76 | RARA (0.49) | RARARARBRARGALDH1A1KDM4E | |
| SCHEMBL24701909 | 0.76 | RARB (0.49) | RARARARBRARGCYP26A1CYP26B1 | |
| SCHEMBL3412594 | 0.72 | ALDH1A1 (0.78) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL442351 | 0.72 | ALDH1A1 (0.83) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL30413338 | 0.72 | ALDH1A1 (0.83) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL2893484 | 0.72 | ALDH1A1 (0.83) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 | |
| SCHEMBL29165604 | 0.72 | ALDH1A1 (0.83) | ALDH1A1CYP3A4HSD17B10ALOX15CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129116-A1 | INDOLO[3.2.1-JK]CARBAZOLE-6-CARBONITRILE DERIVATIVES AS BLUE FLUORESCENT EMITTERS FOR USE IN OLEDS | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129113-A1 | NITROGENOUS HETEROAROMATIC COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-06-23 | — | — | WO | disclosed |