SCHEMBL447737

SCHEMBL447737

CC1(C)CCC(C)(C)c2cc(N)ccc21

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RXRA P19793 14/20 0.44
RARB P10826 11/20 0.44
RXRB P28702 10/20 0.44
RARG P13631 10/20 0.44
RXRG P48443 6/20 0.44
RARA P10276 7/20 0.42
CYP26A1 O43174 3/20 0.41
CYP3A4 P08684 2/20 0.41
CRABP2 P29373 1/20 0.41
CYP26B1 Q9NR63 1/20 0.41
MEN1 O00255 1/20 0.39
ALDH1A1 P00352 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP2C19 P33261 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29707990 1.00 RXRA (0.44) RXRARARBRXRBRARGRXRG
SCHEMBL9446453 0.86 KDM4E (0.38) RXRARARBRXRBRARGRXRG
SCHEMBL24524497 0.81 RARA (0.49) RXRARARBRXRBRARGRXRG
SCHEMBL28921096 0.80 RARB (0.47) RXRARARBRXRBRARGRXRG
SCHEMBL13636819 0.79 RARB (0.63) RXRARARBRARGRARACYP26A1
SCHEMBL29549031 0.78 BACE1 (0.33) CYP3A4MEN1ALDH1A1MAPK1KMT2A
SCHEMBL31534581 0.78 KDM4E (0.36) CYP3A4MEN1ALDH1A1TSHRKMT2A
SCHEMBL11309510 0.78 KDM4E (0.39) MEN1ALDH1A1KMT2A
SCHEMBL806947 0.78 KDM4E (0.36) CYP3A4MEN1ALDH1A1TSHRKMT2A
SCHEMBL9326911 0.78 BACE1 (0.33) CYP3A4MEN1ALDH1A1MAPK1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 239 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552818-B2 Polycyclic compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2026-02-17 US disclosed
US-12435098-B2 Heterocyclic compound and organic light-emitting device comprising same LG CHEM, LTD. (KR) 2025-10-07 US disclosed
US-20250263429-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2025-08-21 US disclosed
US-20240360114-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF Sironax Ltd. (KY) 2024-10-31 US disclosed
EP-3919500-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2024-08-28 EP disclosed
US-20240196735-A1 Organic Compound, Organic Light Emitting Diode and Organic Light Emitting Device Having the Compound LG DISPLAY CO., LTD. (US) 2024-06-13 US disclosed
WO-2024071860-A1 INK COMPOSITION, ORGANIC LIGHT-EMITTING DEVICE USING SAME, AND MANUFACTURING METHOD THEREFOR 주식회사 엘지화학 2024-04-04 WO disclosed
EP-3909958-B1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEMICAL LTD (KR) 2023-12-27 EP disclosed
EP-4273151-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME Lg Chem, Ltd. (KR) 2023-11-08 EP disclosed
US-20230348399-A1 NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2023-11-02 US disclosed
EP-0410358-A1 Aromatic carboxylic acid amides, their preparation and their use as medicines F. HOFFMANN-LA ROCHE AG (CH) 1991-01-30 EP disclosed
EP-0170105-B1 BENZOIC ACID DERIVATIVES Shudo, Koichi, Prof. Dr. (JP) 1990-10-17 EP disclosed
EP-0386451-A1 Oxygen-bearing diphenyl heteroalkanes, process for their preparation and use BASF Aktiengesellschaft (DE) 1990-09-12 EP disclosed
EP-0386452-A1 Diphenyl heteroalkyl derivatives, their preparation and medicinal and cosmetic preparations prepared therefrom BASF Aktiengesellschaft (DE) 1990-09-12 EP disclosed
US-4703110-A Benzoic acid derivatives having a para substituent which is a substituted phenyl group connected by a linking radical; useful in neoplastic cell differentiation and diagnosis Shudo, Koichi (JP) 1987-10-27 US disclosed
EP-0170105-A2 Benzoic acid derivatives Shudo, Koichi, Prof. Dr. (JP) 1986-02-05 EP disclosed
EP-0137010-A4 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES. STANFORD RES INST INT (US) 1985-08-12 EP disclosed
EP-0137010-A1 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES SRI INTERNATIONAL (US) 1985-04-17 EP disclosed
WO-1984003505-A1 NAPHTHYL OR TETRAHYDRONAPHTHYL-SUBSTITUTED NAPHTHOIC ACID AND DE RIVATES STANFORD RES INST INT (US) 1984-09-13 WO disclosed
US-4454341-A ANTITUMOR, SKIN DISORDERS SRI INTERNATIONAL (US) 1984-06-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263429-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, OPRD1 RXRA 107/4885RARB 52/4885RXRB 83/4885
US-12552818-B2 Polycyclic compounds for organic electroluminescent devices SCO2, ESRRA, LBR RXRA 344/4885RARB 609/4885RXRB 383/4885
US-20240360114-A1 FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF AIFM2, GPX1, GPX4 RXRA 674/4885RARB 574/4885RXRB 502/4885
US-20240196735-A1 Organic Compound, Organic Light Emitting Diode and Organic Light Emitting Device Having the Compound L3MBTL1, TELO2, OCIAD2 RXRA 1556/4885RARB 1698/4885RXRB 1912/4885
US-12435098-B2 Heterocyclic compound and organic light-emitting device comprising same CRKL, AHR, ATXN2L RXRA 345/4885RARB 2226/4885RXRB 256/4885
US-20230348399-A1 NOVEL PYRIMIDINE DERIVATIVE AND USE THEREOF LRRK2, PFKL, PDK3 RXRA 3013/4885RARB 3113/4885RXRB 2637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.