Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MARK4 | Q96L34 | 1/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.48 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30213498 | 0.92 | KDM4E (0.56) | P2RX4PTGS2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL12611201 | 0.92 | KDM4E (0.56) | P2RX4PTGS2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL29717634 | 0.92 | KDM4E (0.56) | P2RX4PTGS2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL11382265 | 0.89 | ALDH1A1 (0.68) | P2RX4PTGS2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14160805 | 0.84 | KDM4E (0.62) | ALDH1A1KMT2AHPGDKDM4EHSD17B10 | |
| SCHEMBL6152266 | 0.84 | L3MBTL1 (0.76) | P2RX4PTGS2L3MBTL1ALDH1A1KMT2A | |
| SCHEMBL14160792 | 0.84 | PSEN1 (0.57) | P2RX4PTGS2ALDH1A1CNR2 | |
| SCHEMBL13386557 | 0.83 | ALDH1A1 (0.71) | P2RX4ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL28948755 | 0.82 | DYRK1A (0.58) | L3MBTL1ALDH1A1KMT2AHPGDKDM4E | |
| SCHEMBL14280388 | 0.82 | P2RX4 (0.77) | P2RX4ALDH1A1KMT2AACHETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115698190-B | Light stability simulation of macular pigment | 强生视力健公司 | 2025-06-17 | — | — | CN | claimed |
| CN-115698190-B | Light stability simulation of macular pigment | 强生视力健公司 | 2025-06-17 | — | — | CN | disclosed |
| US-20250189826-A1 | OPHTHALMIC DEVICES CONTAINING PHOTOSTABLE MIMICS OF MACULAR PIGMENT AND OTHER VISIBLE LIGHT FILTERS | JOHNSON & JOHNSON VISION CARE, INC. | 2025-06-12 | — | — | US | disclosed |
| CN-119365797-A | Ophthalmic devices comprising light stable mimics of macular pigments and other visible light filters | 强生视力健公司 | 2025-01-24 | — | — | CN | disclosed |
| CN-115698190-A | Photostable simulation of macular pigment | 强生视力健公司 | 2023-02-03 | — | — | CN | disclosed |
| US-20220194944-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | JOHNSON & JOHNSON VISION CARE, INC. | 2022-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220194944-A1 | PHOTOSTABLE MIMICS OF MACULAR PIGMENT | CRY1, PDE6C, PDE6A | P2RX4 1069/4885PTGS2 1212/4885L3MBTL1 2761/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.