Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | TACR1 | P25103 | 6/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.30 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.30 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.30 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.30 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.30 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24527120 | 0.85 | MMP9 (0.37) | MMP9KDM4EPKMROCK2 | |
| SCHEMBL24526756 | 0.82 | TACR1 (0.35) | TACR1JAK2NTRK1ROCK2 | |
| SCHEMBL29759291 | 0.82 | TACR1 (0.35) | TACR1JAK2NTRK1ROCK2 | |
| SCHEMBL24527025 | 0.80 | UCHL1 (0.38) | TACR1JAK2NTRK1ROCK2 | |
| SCHEMBL24526758 | 0.78 | MMP9 (0.37) | MMP9KDM4EPKM | |
| SCHEMBL29759170 | 0.75 | PRMT5 (0.43) | KDM4EPKMCACNA1GCACNA1HCACNA1I | |
| SCHEMBL24526523 | 0.75 | PRMT5 (0.43) | KDM4EPKMCACNA1GCACNA1HCACNA1I | |
| SCHEMBL24527003 | 0.73 | GRIN3B (0.35) | CACNA1GCACNA1HCACNA1IGRIN3BGRIN1 | |
| SCHEMBL456786 | 0.73 | AR (0.36) | TACR1GPR119 | |
| SCHEMBL12477897 | 0.73 | AR (0.36) | TACR1GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129047-A2 | NOVEL MODULATORS OF THE NMDA RECEPTOR | H. LUNDBECK A/S (DK) | 2022-06-23 | — | — | WO | disclosed |