Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | PAM | P19021 | 1/20 | 0.44 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2452749 | 1.00 | HTR2A (0.50) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| Bromide SCHEMBL2449961 | 0.96 | HTR2A (0.50) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| Water SCHEMBL8528187 | 0.96 | HTR2A (0.50) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| Water SCHEMBL8528185 | 0.96 | HTR2A (0.50) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| Bromide SCHEMBL2449964 | 0.96 | HTR2A (0.50) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| SCHEMBL9178576 | 0.90 | HTR2A (0.46) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| SCHEMBL9178569 | 0.90 | HTR2A (0.46) | HTR2AHIF1AIDO1PAMCHRNA7 | |
| Hydrochloric Acid SCHEMBL2447465 | 0.84 | HIF1A (0.55) | HTR2AHIF1ACHRNA7GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL14839973 | 0.84 | HIF1A (0.55) | HTR2AHIF1ACHRNA7GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL7804921 | 0.83 | GRIK1 (0.49) | HTR2AGRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10928728-B2 | Photoactivable nitrogen bases | BASF SE (DE) | 2021-02-23 | — | — | US | disclosed |
| US-20210033972-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2021-02-04 | — | — | US | disclosed |
| US-10139741-B2 | Charge transport substance, electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2018-11-27 | — | — | US | disclosed |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9921477-B2 | Photoactivable nitrogen bases | BASE SE (DE) | 2018-03-20 | — | — | US | disclosed |
| US-9709906-B2 | Charge transport substance, electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus | MITSUBISHI CHEMICAL CORPORATION (JP) | 2017-07-18 | — | — | US | disclosed |
| EP-2698671-B1 | CHARGE-TRANSPORTING SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY CARTRIDGE, AND IMAGING DEVICE | MITSUBISHI CHEM CORP (JP) | 2016-04-27 | — | — | EP | disclosed |
| US-20150355559-A1 | CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2015-12-10 | — | — | US | disclosed |
| US-20140065532-A1 | CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | MITSUBISHI CHEMICAL CORPORATION (JP) | 2014-03-06 | — | — | US | disclosed |
| US-8663882-B2 | Electrophotographic photosensitive body, image-forming device using same and cartridge | MITSUBISHI CHEMICAL CORPORATION (JP) | 2014-03-04 | — | — | US | disclosed |
| WO-1998041524-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMINO ALKENES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-09-24 | — | — | WO | disclosed |
| WO-1998008505-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 1998-03-05 | — | — | WO | disclosed |
| US-5508424-A | REDUCED SIDE EFFECTS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0690842-A1 | 4-ARYLISOINDOLE ANALGESICS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5389486-A | A mixtures consisting of a binders and a colorless phosphonium compounds charge control agents; metal-free, stability, good dispersibility in binders; copying machine | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1995-02-14 | — | — | US | disclosed |
| WO-1994022823-A1 | 4-ARYLISOINDOLE ANALGESICS | ORTHO PHARMACEUTICAL CORPORATION (US) | 1994-10-13 | — | — | WO | disclosed |
| US-4980280-A | Fluorescent cholesterol-like compounds for use in determining cholesterol levels and properties and the properties of cell membranes | UNIVERSITY OF OTTAWA/UNIVERSITE D'OTTAWA (CA) | 1990-12-25 | — | — | US | disclosed |
| US-4879069-A | DIAGNOSIS OF CHOLESTEROL LEVEL | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 1989-11-07 | — | — | US | disclosed |
| US-4443605-A | ANALGESICS | MILES LABORATORIES, INC. (US) | 1984-04-17 | — | — | US | disclosed |
| US-4440931-A | NARCOTIC ANALGESICS | MILES LABORATORIES, INC. (US) | 1984-04-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210033972-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, ARNT, NR0B1 | HTR2A 1023/4885HIF1A 1258/4885IDO1 2539/4885 |
| US-10928728-B2 | Photoactivable nitrogen bases | CBR1, NR0B1, NR0B2 | HTR2A 959/4885HIF1A 1136/4885IDO1 2194/4885 |
| US-10139741-B2 | Charge transport substance, electrophotographic photoreceptor, electrophotographic photoreceptor cartridge, and image-forming apparatus | PDE6C, SLC18A2, SLC1A2 | HTR2A 701/4885HIF1A 3042/4885IDO1 3586/4885 |
| US-20150355559-A1 | CHARGE TRANSPORT SUBSTANCE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE-FORMING APPARATUS | PDE6C, SLC18A2, SLC1A2 | HTR2A 701/4885HIF1A 3042/4885IDO1 3586/4885 |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, NR0B1, NR0B2 | HTR2A 959/4885HIF1A 1136/4885IDO1 2194/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.