Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 8/20 | 0.34 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.31 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL14839973 | 1.00 | HIF1A (0.55) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL8925807 | 0.95 | HIF1A (0.55) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL11255368 | 0.86 | HIF1A (0.46) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL2445999 | 0.86 | HIF1A (0.46) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL2446001 | 0.86 | HIF1A (0.46) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Bromide SCHEMBL16004643 | 0.84 | HIF1A (0.44) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL2452746 | 0.84 | HTR2A (0.50) | HIF1AHTR2ACHRNA7GRIK1GRIK2 | |
| Bromide SCHEMBL11584557 | 0.84 | HIF1A (0.44) | HIF1AALDH1A1CYP1A2CYP2D6TSHR | |
| Hydrochloric Acid SCHEMBL2452749 | 0.84 | HTR2A (0.50) | HIF1AHTR2ACHRNA7GRIK1GRIK2 | |
| Hydrochloric Acid SCHEMBL11732846 | 0.83 | HIF1A (0.43) | HIF1AALDH1A1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10928728-B2 | Photoactivable nitrogen bases | BASF SE (DE) | 2021-02-23 | — | — | US | disclosed |
| US-20210033972-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2021-02-04 | — | — | US | disclosed |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2018-08-02 | — | — | US | disclosed |
| US-9921477-B2 | Photoactivable nitrogen bases | BASE SE (DE) | 2018-03-20 | — | — | US | disclosed |
| EP-2145231-B1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2011-09-14 | — | — | EP | disclosed |
| US-20100105794-A1 | PHOTOACTIVABLE NITROGEN BASES | CIBA CORPORATION (US) | 2010-04-29 | — | — | US | disclosed |
| EP-2145231-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (DE) | 2010-01-20 | — | — | EP | disclosed |
| WO-2008119688-A1 | PHOTOACTIVABLE NITROGEN BASES | BASF SE (CH) | 2008-10-09 | — | — | WO | disclosed |
| EP-0970085-B1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON ALPHA-AMINO ALKENES | CIBA SC HOLDING AG (CH) | 2002-07-24 | — | — | EP | disclosed |
| US-6087070-A | AS PHOTOINITIATORS FOR BASE-CATALYZABLE REACTIONS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-07-11 | — | — | US | disclosed |
| EP-0970085-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON $g(a)-AMINO ALKENES | Ciba SC Holding AG (CH) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998041524-A1 | PHOTOACTIVATABLE NITROGEN-CONTAINING BASES BASED ON α-AMINO ALKENES | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 1998-09-24 | — | — | WO | disclosed |
| US-5097022-A | Bisazo pigments for use in electrophotographic photoconductors | RICOH COMPANY, LTD. (JP) | 1992-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210033972-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, ARNT, NR0B1 | HIF1A 1258/4885ALDH1A1 1659/4885CYP1A2 73/4885 |
| US-10928728-B2 | Photoactivable nitrogen bases | CBR1, NR0B1, NR0B2 | HIF1A 1136/4885ALDH1A1 1733/4885CYP1A2 81/4885 |
| US-20180217498-A1 | PHOTOACTIVABLE NITROGEN BASES | CBR1, NR0B1, NR0B2 | HIF1A 1136/4885ALDH1A1 1733/4885CYP1A2 81/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.