Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25008587 | 0.76 | TRPV4 (0.41) | TRPV4 | |
| SCHEMBL21125124 | 0.76 | TRPV4 (0.41) | TRPV4 | |
| SCHEMBL31522552 | 0.76 | TRPV4 (0.41) | TRPV4 | |
| SCHEMBL21746057 | 0.73 | APLNR (0.44) | — | |
| SCHEMBL29435725 | 0.73 | APLNR (0.44) | — | |
| SCHEMBL22895423 | 0.73 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL595417 | 0.71 | CA12 (0.39) | — | |
| SCHEMBL9839014 | 0.71 | — | — | |
| SCHEMBL16128777 | 0.71 | — | — | |
| SCHEMBL595295 | 0.71 | KDM4E (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129913-A1 | ALKYNE DERIVATIVES AS INHIBITORS OF C-ABL | BENEVOLENTAI BIO LIMITED (GB) | 2022-06-23 | — | — | WO | disclosed |