SCHEMBL25008587

SCHEMBL25008587

OC(O)c1ccc(S)cn1

nearest known ligand 0.41

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV4 Q9HBA0 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2213350 0.82 TRPV4 (0.39) TRPV4
SCHEMBL31522552 0.76 TRPV4 (0.41) TRPV4
SCHEMBL24528577 0.76 TRPV4 (0.46) TRPV4
SCHEMBL2897054 0.73 ESR1 (0.50)
SCHEMBL14950021 0.71 CCR1 (0.48)
SCHEMBL9603432 0.67
SCHEMBL14946815 0.67 LMNA (0.38)
SCHEMBL30827553 0.67 P4HA1 (0.57)
SCHEMBL10834459 0.66
SCHEMBL2213351 0.64 TRPV4 (0.39) TRPV4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023011573-A1 AROMATIC ACETYLENE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF 浙江海正药业股份有限公司 2023-02-09 WO disclosed