Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.37 |
| ▸ | TRIM58 | Q8NG06 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528628 | 0.85 | ADORA2A (0.34) | ADORA2AADORA1RAD52 | |
| SCHEMBL24528642 | 0.84 | SCN9A (0.41) | SCN9ATRIM58 | |
| SCHEMBL24528590 | 0.84 | ADORA2A (0.40) | ADORA2AADORA1 | |
| SCHEMBL24528664 | 0.70 | ADORA2A (0.34) | ADORA2A | |
| SCHEMBL24528643 | 0.69 | NUDT1 (0.38) | — | |
| SCHEMBL24528587 | 0.68 | KDM4E (0.40) | RAD52 | |
| SCHEMBL29681009 | 0.68 | KDM4E (0.40) | RAD52 | |
| SCHEMBL3681700 | 0.65 | ADORA2A (0.73) | SCN9AADORA2AADORA1RAD52 | |
| SCHEMBL24528588 | 0.64 | ALDH1A1 (0.36) | — | |
| SCHEMBL24528635 | 0.63 | BPTF (0.38) | ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |