Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | NPY1R | P25929 | 1/20 | 0.31 |
| ▸ | NPY2R | P49146 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528693 | 0.99 | TLR9 (0.31) | TLR9MAOBTHRBNPY1RNPY2R | |
| SCHEMBL24528701 | 0.88 | KDM4E (0.33) | MAOBALDH1A1LMNAMEN1PSMD14 | |
| SCHEMBL24528686 | 0.86 | RAB9A (0.35) | TLR9L3MBTL1ALDH1A1 | |
| SCHEMBL24528611 | 0.77 | ADK (0.35) | L3MBTL1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL24528695 | 0.75 | KDM4E (0.34) | TLR9MAOBTHRBNPY1RNPY2R | |
| SCHEMBL24528639 | 0.75 | ATM (0.37) | TLR9MAOBALDH1A1LMNA | |
| SCHEMBL29680708 | 0.75 | GSK3B (0.41) | ALDH1A1MEN1KMT2A | |
| SCHEMBL24528677 | 0.75 | KDM4E (0.34) | TLR9MAOBALDH1A1LMNA | |
| SCHEMBL29680812 | 0.74 | GSK3B (0.40) | ALDH1A1MEN1KMT2A | |
| SCHEMBL24528655 | 0.73 | KDM4E (0.34) | TLR9THRBNPY1RNPY2RL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |