Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24528640 | 0.86 | TLR9 (0.32) | ALDH1A1L3MBTL1TLR9 | |
| SCHEMBL24528693 | 0.85 | TLR9 (0.31) | ALDH1A1L3MBTL1TLR9 | |
| SCHEMBL24528690 | 0.78 | TLR9 (0.41) | RAB9ASMN1; SMN2KDM4EALDH1A1NPC1 | |
| SCHEMBL24528661 | 0.78 | RAD52 (0.36) | RAB9APOLBNPSR1HTTSMN1; SMN2 | |
| SCHEMBL29680767 | 0.78 | KDM5B (0.42) | KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL24528701 | 0.76 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL24528611 | 0.76 | ADK (0.35) | RAB9APOLBNPSR1HTTSMN1; SMN2 | |
| SCHEMBL24528648 | 0.76 | RAD52 (0.37) | RAB9APOLBNPSR1HTTSMN1; SMN2 | |
| SCHEMBL29680554 | 0.76 | RAD52 (0.37) | RAB9APOLBNPSR1HTTSMN1; SMN2 | |
| SCHEMBL24528607 | 0.73 | TLR9 (0.36) | RAB9APOLBNPSR1HTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129376-A1 | 6-6 OR 5-6 FUSED BICYCLIC COMPOUNDS COMPRISING A PYRI(MI)DINE RING USEFUL IN THE|TREATMENT OF INFECTIOUS DISEASES | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2022-06-23 | — | — | WO | disclosed |