Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 2/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24762157 | 0.78 | FPR2 (0.36) | HRH3CRBNSLC6A2SLC6A4HAO1 | |
| SCHEMBL1704613 | 0.75 | HTR6 (0.57) | HTR2CMAPK1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL24529835 | 0.75 | HTR2C (0.56) | HTR2CMAPK1HRH3HRH1HRH4 | |
| Hydrochloric Acid SCHEMBL23303031 | 0.73 | HTR6 (0.58) | HTR2CMAPK1SLC6A2SLC6A4KCNH2 | |
| SCHEMBL20291420 | 0.73 | EPHX2 (0.58) | — | |
| SCHEMBL6901785 | 0.72 | MAPT (0.43) | CRBNKCNH2PTGIR | |
| SCHEMBL26448460 | 0.71 | HTR2C (0.51) | HTR2CHRH3HRH1HRH4CYP3A4 | |
| SCHEMBL24393407 | 0.71 | BCHE (0.57) | HTR2CMAPK1HRH3SLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL70804 | 0.71 | HTR2C (0.51) | HTR2CCYP2C19DDB1CRBNSLC6A2 | |
| SCHEMBL6785503 | 0.70 | HDAC4 (0.62) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022130352-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2022-06-23 | — | — | WO | disclosed |