Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 4/20 | 0.54 |
| ▸ | PRKAG1 | P54619 | 4/20 | 0.54 |
| ▸ | PRKAA2 | P54646 | 4/20 | 0.54 |
| ▸ | PRKAA1 | Q13131 | 4/20 | 0.54 |
| ▸ | PRKAG3 | Q9UGI9 | 4/20 | 0.54 |
| ▸ | PRKAG2 | Q9UGJ0 | 4/20 | 0.54 |
| ▸ | PRKAB1 | Q9Y478 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29716517 | 0.91 | SIGMAR1 (0.52) | SIGMAR1OPRL1MEN1LMNATSHR | |
| SCHEMBL24529883 | 0.88 | SIGMAR1 (0.66) | SIGMAR1OPRL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL24529983 | 0.84 | MGLL (0.55) | — | |
| SCHEMBL29716308 | 0.82 | RHOC (0.54) | LMNAKMT2A | |
| SCHEMBL24529795 | 0.82 | RHOC (0.54) | LMNAKMT2A | |
| SCHEMBL29716268 | 0.82 | SIGMAR1 (0.58) | SIGMAR1OPRL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL24529969 | 0.82 | SIGMAR1 (0.58) | SIGMAR1OPRL1PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL29844154 | 0.81 | RBP4 (0.49) | LMNA | |
| SCHEMBL23577525 | 0.81 | RBP4 (0.49) | LMNA | |
| SCHEMBL1218956 | 0.81 | SIGMAR1 (0.68) | SIGMAR1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022130352-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2022-06-23 | — | — | WO | claimed |
| WO-2022130352-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022130352-A1 | NOVEL COMPOUNDS SUITABLE FOR THE TREATMENT OF DYSLIPIDEMIA | CADILA HEALTHCARE LIMITED (IN) | 2022-06-23 | — | — | WO | disclosed |