Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.57 |
| ▸ | HRH3 | Q9Y5N1 | 13/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | HRH2 | P25021 | 1/20 | 0.54 |
| ▸ | HRH1 | P35367 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD1 | P21728 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7247185 | 0.94 | HRH3 (0.60) | LTA4HHRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL24529993 | 0.90 | LTA4H (0.69) | LTA4HHRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL6785023 | 0.84 | LMNA (0.75) | LTA4HHRH3MEN1KMT2AALDH1A1 | |
| SCHEMBL31706379 | 0.82 | HRH3 (0.76) | HRH3MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL16314571 | 0.81 | HRH3 (0.58) | LTA4HHRH3MEN1KMT2AHRH2 | |
| SCHEMBL16914838 | 0.81 | HRH3 (0.73) | HRH3MEN1KMT2AHRH2HRH1 | |
| SCHEMBL16358244 | 0.81 | HRH3 (0.58) | HRH3MEN1KMT2AALDH1A1HRH2 | |
| SCHEMBL22266155 | 0.81 | LTA4H (0.62) | LTA4HHRH3 | |
| SCHEMBL28285428 | 0.80 | HRH3 (0.70) | HRH3MEN1KMT2AHRH2HRH1 | |
| SCHEMBL5752269 | 0.79 | LTA4H (0.64) | LTA4HHRH3MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025217552-A1 | 2-(TERT-BUTYL)-4-METHYLPHENYL APPENDED 1,4-DIAZEPANE BASED NOVEL TFEB ACTIVATING COMPOUNDS AS AUTOPHAGY MODULATORS FOR NEURODEGENERATIVE DISORDERS INCLUDING ALZHEIMER'S DISEASE (AD) | MEMORIAL SLOAN-KETTERING CANCER CENTER (US) | 2025-10-16 | — | — | WO | disclosed |