Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | PLA2G4B | P0C869 | 6/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL29441580 | 0.90 | TSHR (0.37) | NNMTLMNA | |
| SCHEMBL1274 | 0.82 | — | — | |
| SCHEMBL28761094 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL4602188 | 0.80 | NNMT (0.39) | NNMTLMNAL3MBTL1ADORA3PARP10 | |
| Bromide SCHEMBL21598344 | 0.80 | — | — | |
| Fluoride SCHEMBL28397310 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL3825719 | 0.80 | — | — | |
| Methylsulfanylmethane SCHEMBL4600651 | 0.79 | NNMT (0.40) | NNMTLMNAADORA3PARP10 | |
| SCHEMBL9101778 | 0.78 | HSD17B3 (0.41) | L3MBTL1HCAR2CES2CES1 | |
| Formic Acid SCHEMBL2593165 | 0.75 | NNMT (0.36) | NNMTLMNAADORA3PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-12-01 | — | — | US | disclosed |
| US-8022220-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2011-09-20 | — | — | US | disclosed |
| US-20100010227-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 2010-01-14 | — | — | US | disclosed |
| US-7560561-B2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2009-07-14 | — | — | US | disclosed |
| EP-0877733-B1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | AMR TECHNOLOGY INC (US) | 2006-08-09 | — | — | EP | disclosed |
| US-6974872-B2 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20050272771-A1 | Process for production of piperidine derivatives | AMR TECHNOLOGY, INC. (US) | 2005-12-08 | — | — | US | disclosed |
| EP-1362849-A2 | Process for production of piperidine derivatives | ALBANY MOLECULAR RESEARCH, INC. (US) | 2003-11-19 | — | — | EP | disclosed |
| US-20030171590-A1 | Process for production of piperidine derivatives | APOLLO ADMINISTRATIVE AGENCY LLC, AS SUCCESSOR AGENT | 2003-09-11 | — | — | US | disclosed |
| US-6452011-B1 | NON-SEDATING ANTI-HISTAMINE H1 ANTAGONIST | ALBANY MOLECULAR RESEARCH, INC. | 2002-09-17 | — | — | US | disclosed |
| US-6448406-B1 | IMPROVED PROCESS FOR PREPARATION OF TERFENADINE CARBOXYLIC ACID METABOLITE AND CAREBASTINE DERIVATIVES; HISTAMINE H1 RECEPTOR BLOCKING AND CALCIUM ANTAGONISTS; RESPIRATORY, ALLERGIC, AND CARDIOVASCULAR DISEASE STATES | ALBANY MOLECULAR RESEARCH, INC. | 2002-09-10 | — | — | US | disclosed |
| US-6201124-B1 | CONVERTING, WITH A PIPERIDINE COMPOUND, REGIOISOMERS UNDER NON-FRIEDEL-CRAFTS REACTION CONDITIONS | ALBANY MOLECULAR RESEARCH, INC. | 2001-03-13 | — | — | US | disclosed |
| EP-0877733-A4 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RES INC (US) | 1999-03-31 | — | — | EP | disclosed |
| EP-0877733-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997022344-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | ALBANY MOLECULAR RESEARCH, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110295014-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | OR10J3, NR1H2, NR1H3 | FFAR3 604/4885HDAC3 326/4885HDAC1 637/4885 |
| US-20050272771-A1 | Process for production of piperidine derivatives | HRH4, CBR1, CBR3 | FFAR3 999/4885HDAC3 389/4885HDAC1 576/4885 |
| US-20030171590-A1 | Process for production of piperidine derivatives | NR4A1, NR4A2, NR5A2 | FFAR3 1329/4885HDAC3 162/4885HDAC1 531/4885 |
| US-20100010227-A1 | PROCESS FOR PRODUCTION OF PIPERIDINE DERIVATIVES | DDC, HPD, ALDH7A1 | FFAR3 1698/4885HDAC3 457/4885HDAC1 500/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.