SCHEMBL2453350

SCHEMBL2453350

c1ccc(C2(c3ccccc3)c3ccccc3Nc3ccccc32)cc1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.69
ADORA3 P0DMS8 2/20 0.50
CHRM2 P08172 1/20 0.50
KCNH2 Q12809 1/20 0.50
MAPT P10636 5/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
PDK2 Q15119 1/20 0.40
PDK4 Q16654 1/20 0.40
KDM4E B2RXH2 1/20 0.40
OPRK1 P41145 1/20 0.40
GAA P10253 3/20 0.39
XBP1 P17861 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
MGAM O43451 1/20 0.38
SI P14410 1/20 0.38
MGAM2 Q2M2H8 1/20 0.38
CYP2D6 P10635 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29373003 1.00 LMNA (0.69) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL19318176 0.91 LMNA (0.60) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL9332219 0.84 LMNA (0.54) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL29815212 0.84 LMNA (0.54) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL25310546 0.83 LMNA (0.51) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL13832926 0.83 LMNA (0.51) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL24022093 0.83 LMNA (0.51) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL22100692 0.83 LMNA (0.51) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL23988573 0.83 LMNA (0.51) LMNAADORA3CHRM2KCNH2MAPT
SCHEMBL19001732 0.83 LMNA (0.51) LMNAADORA3CHRM2KCNH2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 382 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11898074-B2 Blue thermally activated delayed fluorescence material, synthesis method thereof, and use thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-02-13 US claimed
CN-117069767-A Benzimidazole compound containing aromatic phosphine group, preparation method and application thereof 黑龙江大学 2023-11-17 CN claimed
CN-113461628-B Chiral thermal activation delayed fluorescence molecule based on [2.2] para-cyclophane and preparation method and application thereof 中国科学院化学研究所 2023-02-03 CN claimed
US-11453691-B2 Method for preparing sensitizing material and organic light emitting diode WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-09-27 US claimed
US-11401465-B2 Thermally activated delayed fluorescent and synthesizing method thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-08-02 US claimed
US-11362284-B2 Efficient blue-green to orange-red thermally activated delayed fluorescence material, manufacture method, and application thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-06-14 US claimed
US-11322694-B2 Electroluminescent material, method for manufacturing same, and light emitting device WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2022-05-03 US claimed
CN-113773331-B Cross-bond energy transfer type Hg2+Fluorescent probe, preparation method and application thereof 吉林大学 2022-04-01 CN claimed
CN-112010806-B Stimulus-response type organic long-afterglow material and preparation method and application thereof 南京邮电大学 2022-03-25 CN claimed
CN-114106028-A Indolocarbazole diboron derivative, and preparation and application thereof 华中科技大学 2022-03-01 CN claimed
CN-109722237-A A kind of fluorescence probe based on condensed ring oxidation of thiophene and its application in cell imaging 华南理工大学 2019-05-07 CN claimed
CN-109627265-A A kind of preparation method and Organic Light Emitting Diode of sensitized material 武汉华星光电半导体显示技术有限公司 2019-04-16 CN claimed
CN-109369652-A A kind of blue light thermal activation delayed fluorescence material and its application 武汉华星光电半导体显示技术有限公司 2019-02-22 CN claimed
CN-109337676-A A kind of dark blue photo-thermal activation delayed fluorescence material and its application 武汉华星光电半导体显示技术有限公司 2019-02-15 CN claimed
CN-109293583-A A kind of heterocyclic compound containing quinazoline and its application in organic electro-optic device 西安瑞联新材料股份有限公司 2019-02-01 CN claimed
CN-108864350-A Thermal activation delayed fluorescence material, synthetic method, OLED luminescent device, display device 武汉华星光电半导体显示技术有限公司 2018-11-23 CN claimed
CN-108658960-A A kind of thermal activation delayed fluorescence material and its application 中节能万润股份有限公司 2018-10-16 CN claimed
CN-108586353-A A kind of luminous organic material and its preparation method and application based on anthracene and its derivative 华南理工大学 2018-09-28 CN claimed
CN-108069951-A Electroluminescent organic material and preparation method of the one kind based on benzoyl derivatives 华南理工大学 2018-05-25 CN claimed
CN-106566533-A Condensed ring oxidized thiophene-based organic luminescent material, and preparation method and application thereof 华南理工大学 2017-04-19 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11453691-B2 Method for preparing sensitizing material and organic light emitting diode DBF4, TST, HRH4 LMNA 4542/4885ADORA3 4529/4885CHRM2 1638/4885
US-11322694-B2 Electroluminescent material, method for manufacturing same, and light emitting device GPR17, CALCR, TAAR1 LMNA 2287/4885ADORA3 147/4885CHRM2 370/4885
US-11362284-B2 Efficient blue-green to orange-red thermally activated delayed fluorescence material, manufacture method, and application thereof TEAD2, TEAD1, MAP1LC3B LMNA 917/4885ADORA3 3866/4885CHRM2 2292/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.