SCHEMBL24533736

SCHEMBL24533736

O=C(COc1ccccc1)Oc1cc(OC(=O)COc2ccccc2)cc(OC(=O)COc2ccccc2)c1

nearest known ligand 0.65

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.61
KMT2A Q03164 4/20 0.54
MEN1 O00255 3/20 0.54
HPGD P15428 3/20 0.54
ALDH1A1 P00352 2/20 0.54
GAA P10253 2/20 0.53
NPC1 O15118 2/20 0.51
TDP1 Q9NUW8 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
MAPT P10636 3/20 0.51
KDM4E B2RXH2 1/20 0.51
RAB9A P51151 1/20 0.51
LMNA P02545 2/20 0.50
ALPL P05186 1/20 0.49
ALPI P09923 1/20 0.49
ALPG P10696 1/20 0.49
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL472034 0.92 ALOX15 (0.65) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL7653097 0.84 PTPN7 (0.65) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL10784303 0.83 MAPT (0.64) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL10199128 0.82 GAA (0.76) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL16358912 0.82 ALOX15 (0.53) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL10595768 0.82 L3MBTL1 (0.58) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL24844739 0.82 GAA (0.76) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL10597791 0.82 GAA (0.76) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL28050813 0.82 PKM (0.66) ALOX15KMT2AMEN1HPGDALDH1A1
SCHEMBL264346 0.81 ALOX15 (0.68) ALOX15KMT2AMEN1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220197140-A1 ALCOHOL COMPOUND, CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2022-06-23 US disclosed