SCHEMBL472034

SCHEMBL472034

O=C(COc1ccccc1)Oc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.65
GAA P10253 2/20 0.58
LMNA P02545 1/20 0.58
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
HPGD P15428 3/20 0.56
ALDH1A1 P00352 2/20 0.56
ALPL P05186 1/20 0.52
ALPI P09923 1/20 0.52
ALPG P10696 1/20 0.52
MAPT P10636 2/20 0.50
NPC1 O15118 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
CYP19A1 P11511 1/20 0.50
KDM4E B2RXH2 1/20 0.50
RAB9A P51151 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24533736 0.92 ALOX15 (0.61) ALOX15GAALMNAKMT2AMEN1
SCHEMBL10784303 0.91 MAPT (0.64) ALOX15GAALMNAKMT2AMEN1
SCHEMBL28050813 0.89 PKM (0.66) ALOX15GAALMNAKMT2AMEN1
SCHEMBL10199128 0.89 GAA (0.76) ALOX15GAALMNAKMT2AMEN1
SCHEMBL10595768 0.89 L3MBTL1 (0.58) ALOX15GAALMNAKMT2AMEN1
SCHEMBL24844739 0.89 GAA (0.76) ALOX15GAALMNAKMT2AMEN1
SCHEMBL10597791 0.89 GAA (0.76) ALOX15GAALMNAKMT2AMEN1
SCHEMBL16358912 0.89 ALOX15 (0.53) ALOX15GAALMNAKMT2AMEN1
SCHEMBL10625899 0.85 SMN1; SMN2 (0.66) GAALMNAKMT2AMEN1HPGD
SCHEMBL8864820 0.85 ALDH1A1 (0.50) ALOX15GAALMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 361 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111511809-B Curing agent composition and resin composition containing the same 赫克塞尔合成有限公司 2024-08-16 CN claimed
CN-110740725-B Composition containing benzoic acid amide compound and cyclodextrin solubilizer 株式会社爱茉莉太平洋 2024-01-12 CN claimed
CN-111218323-B Environment-friendly lubricating oil and preparation method thereof 辽宁大学 2022-06-14 CN claimed
CN-111218323-A Environment-friendly lubricating oil and preparation method thereof 辽宁大学 2020-06-02 CN claimed
CN-111187290-A Environment-friendly novel ionic liquid and preparation method and application thereof 辽宁大学 2020-05-22 CN claimed
CN-108586229-A The synthesis of diphenyl hydroxyacetic acid 烟台智本知识产权运营管理有限公司 2018-09-28 CN claimed
US-8557730-B2 Composition and process for making the composition MOLYCORP MINERALS, LLC (US) 2013-10-15 US claimed
CN-103119208-A A biocidal polyolefin yarn with 3-12 filaments VESTERGAARD FRANDSEN SA 2013-05-22 CN claimed
US-8252087-B2 Process and apparatus for treating a gas containing a contaminant MOLYCORP MINERALS, LLC (US) 2012-08-28 US claimed
US-8114775-B2 Dihydroxy enol compounds used in chemical mechanical polishing compositions having metal ion oxidizers DUPONT AIR PRODUCTS NANOMATERIALS, LLC (US) 2012-02-14 US claimed
US-5621006-A TOPICALLY APPLYING IN A VEHICLE, E.G. HYDROXYACIDS, KETOACIDS AND SALTS, ESTERS THEREOF YU RUEY J (US) 1997-04-15 US claimed
EP-0599819-B1 Use of hydroxycarboxylic acids and derivatives for the preparation of topical dermatologic compositions for the treatment of wrinkles SCOTT EUGENE J VAN (US) 1997-04-02 EP claimed
US-5561158-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA, INCORPORATED 1996-10-01 US claimed
US-5561157-A INCLUDES ORGANIC ALPHA AND BETA HYDROXY OR KETO CARBOXYLIC ACIDS, ESTERS, LACTONES AND/OR SALTS; USED FOR SKIN DISORDERS TRISTRATA INC (US) 1996-10-01 US claimed
US-5554597-A Compositions comprising 2-hydroxycarboxylic acids and related compounds, and methods for alleviating signs of dermatological aging TRISTRATA INC (US) 1996-09-10 US claimed
US-5554652-A TOPICALLY APPLYING MIXTURE TO REDUCE OR PREVENT SKIN DISORDERS TRISTRATA INC (US) 1996-09-10 US claimed
US-5554654-A COMPRISING SALICYLIC ACID, RETINOIC ACID, ERYTHROMYCIN, METRONIDAZOLE, TETRACYCLINE, CLINDAMYCIN, MINOCYCLINE, MECLOCYCLINE OR BENZILIC ACID BY COMBINING WITH 2-HYDROXY ACID, 2-KETOACID, DERIVATIVE THEREOF OR RELATED COMPOUND TRISTRATA INC (US) 1996-09-10 US claimed
EP-0273202-B1 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. SCOTT EUGENE J VAN (US) 1995-06-21 EP claimed
EP-0599819-A2 Additives enhancing topical actions of therapeutic agents Van Scott, Eugene J., Dr. (US) 1994-06-01 EP claimed
EP-0273202-A2 Use of hydroxycarboxylic acids to enhance therapeutic effects of topical compositions for fungal infections and pigmented spots. Van Scott, Eugene J., Dr. (US) 1988-07-06 EP claimed