Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3626865 | 0.86 | POLB (0.44) | POLBALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL30059752 | 0.84 | PTGES2 (0.37) | POLBPDIA6ALDH1A1KDM4ECA1 | |
| SCHEMBL2812505 | 0.83 | POLB (0.41) | POLBALDH1A1L3MBTL1KDM4ELMNA | |
| SCHEMBL11809216 | 0.83 | POLB (0.44) | POLBPDIA6ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL11785640 | 0.81 | POLB (0.54) | POLBKDM4ELMNACA1CA2 | |
| SCHEMBL9282483 | 0.81 | XDH (0.46) | POLBALDH1A1KDM4ESMN1; SMN2MAPK1 | |
| SCHEMBL4462790 | 0.81 | CA2 (0.45) | POLBPDIA6ALDH1A1KDM4ELMNA | |
| SCHEMBL30069489 | 0.80 | KDM4E (0.45) | POLBPDIA6ALDH1A1KDM4ELMNA | |
| SCHEMBL1559677 | 0.80 | KDM4E (0.45) | POLBPDIA6ALDH1A1KDM4ELMNA | |
| SCHEMBL27580944 | 0.80 | L3MBTL1 (0.39) | POLBALDH1A1L3MBTL1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| US-9815765-B2 | Ruthenium polymerisation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2017-11-14 | — | — | US | disclosed |
| EP-3055063-A1 | RUTHENIUM POLYMERISATION CATALYSTS | University Court of The University of St Andrews (GB) | 2016-08-17 | — | — | EP | disclosed |
| US-9233994-B2 | Ruthenium complexes for use in olefin metathesis | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-01-12 | — | — | US | disclosed |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2014-08-14 | — | — | US | disclosed |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2013-06-27 | — | — | US | disclosed |
| WO-2013045876-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2013-04-04 | — | — | WO | disclosed |
| EP-2550284-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | University Court Of The University Of St Andrews (GB) | 2013-01-30 | — | — | EP | disclosed |
| WO-2011117571-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2011-09-29 | — | — | WO | disclosed |
| US-20080312404-A1 | Novel diepoxides and epoxy resins | PEWS R GARTH | 2008-12-18 | — | — | US | disclosed |
| US-7462728-B2 | Diepoxide derivatives of N,N*-disubstituted disulfonamides | PEWS R GARTH | 2008-12-09 | — | — | US | disclosed |
| EP-1487928-B1 | FILM-FORMING POLYMER AND ANTIFOULING PAINT | JOTUN AS (NO) | 2008-08-13 | — | — | EP | disclosed |
| EP-1618157-B1 | USE OF POLYANHYDRIDES IN ANTIFOULING PAINT AND ANTIFOULING PAINT CONTAINING POLYANHYDRIDES | JOTUN AS (NO) | 2007-03-14 | — | — | EP | disclosed |
| US-20060128978-A1 | Diepoxide derivatives of N, N*-disubstituted disulfonamides | PEWS R G | 2006-06-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | POLB 309/4885PDIA6 685/4885ALDH1A1 4132/4885 |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | OSBP, CYCS, OSBPL3 | POLB 1380/4885PDIA6 1500/4885ALDH1A1 4330/4885 |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | POLB 309/4885PDIA6 685/4885ALDH1A1 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.