Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 5/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 4/20 | 0.39 |
| ▸ | NADK | O95544 | 1/20 | 0.38 |
| ▸ | NT5E | P21589 | 2/20 | 0.37 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 2/20 | 0.36 |
| ▸ | SRC | P12931 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.36 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23052587 | 0.89 | NT5E (0.49) | POLBP2RY1ENPP1NT5EP2RX1 | |
| SCHEMBL20324914 | 0.87 | P2RY1 (0.33) | POLBP2RY1P2RY2TRPM2SRC | |
| SCHEMBL20324789 | 0.85 | STING1 (0.31) | POLBP2RY1P2RY2TRPM2SRC | |
| SCHEMBL17106740 | 0.82 | ADRB1 (0.40) | POLBSMN1; SMN2ADORA1PDE4DPDE3A | |
| SCHEMBL20324585 | 0.80 | DNPH1 (0.38) | P2RY1P2RY2TRPM2SRCSMN1; SMN2 | |
| SCHEMBL21637014 | 0.77 | DNPH1 (0.38) | P2RY1P2RY2TRPM2SRCSMN1; SMN2 | |
| SCHEMBL19412763 | 0.76 | AHCY (0.37) | — | |
| SCHEMBL20325339 | 0.75 | POLB (0.31) | POLBP2RY1P2RY2TRPM2SRC | |
| SCHEMBL21943897 | 0.74 | STING1 (0.49) | POLBNT5EP2RY2 | |
| SCHEMBL18521199 | 0.74 | STING1 (0.49) | POLBNT5EP2RY2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022127914-A1 | NUCLEOSIDE-THIODIPHOSPHATE-HEPTOSE COMPOUNDS FOR TREATING CONDITIONS ASSOCIATED WITH ALPK1 ACTIVITY | PYROTECH (BEIJING) BIOTECHNOLOGY CO., LTD. (CN) | 2022-06-23 | — | — | WO | disclosed |