SCHEMBL245409

SCHEMBL245409

COc1ccc(N)cc1C

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.57
MAPT P10636 5/20 0.57
KDM4E B2RXH2 4/20 0.57
LMNA P02545 2/20 0.57
NR4A1 P22736 1/20 0.55
USP2 O75604 1/20 0.53
GAA P10253 2/20 0.52
TSHR P16473 1/20 0.52
MAPK1 P28482 1/20 0.52
HTT P42858 1/20 0.52
CYP3A4 P08684 1/20 0.50
PDE10A Q9Y233 1/20 0.48
CYP19A1 P11511 2/20 0.47
MEN1 O00255 2/20 0.47
THRB P10828 2/20 0.47
KMT2A Q03164 2/20 0.47
ALOX15 P16050 1/20 0.47
CASP1 P29466 1/20 0.46
ACHE P22303 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30473086 0.83 ALDH1A1 (0.56) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL4329985 0.83 ALDH1A1 (0.56) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL5553236 0.82 AR (0.50) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL264325 0.81 MAPT (0.57) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL29377777 0.80 KDM4E (0.67) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL2438047 0.80 KDM4E (0.67) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL77823 0.80 KDM4E (0.67) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL5549511 0.80 TDP1 (0.54) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL10961583 0.80 IDO1 (0.53) ALDH1A1MAPTKDM4ELMNANR4A1
SCHEMBL6011393 0.80 PTGS2 (0.46) ALDH1A1MAPTKDM4ELMNANR4A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 494 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111233774-B Amino pyrimidine compound 鲁南制药集团股份有限公司 2023-04-14 CN claimed
CN-115772093-A Synthesis method of symmetric azobenzene solar thermal fuel 天津大学 2023-03-10 CN claimed
CN-111410738-A Preparation method of amine autocatalytic polyether polyol 山东蓝星东大有限公司 2020-07-14 CN claimed
CN-111233774-A Amino pyrimidine compound 鲁南制药集团股份有限公司 2020-06-05 CN claimed
CN-110467538-A A kind of synthetic method of 2- methyl -4- methoxy diphenylamine SHANDONG EXCERIS CHEMICAL CO LTD 2019-11-19 CN claimed
CN-108218730-B A kind of method that the copper that ligand is recyclable catalyzes and synthesizes 2- methyl -4- methoxy diphenylamine 中山大学 2019-09-24 CN claimed
CN-108033952-B Phenylalanine derivative and the preparation method and application thereof containing triazole ring 山东大学 2019-07-23 CN claimed
CN-109897088-A Phenylalanine derivative and the preparation method and application thereof containing N- (2- oxoethyl) benzsulfamide 山东大学 2019-06-18 CN claimed
CN-109836477-A Phenylalanine derivative and the preparation method and application thereof containing benzothiadiazine -3- ketone 1,1- dioxide 山东大学 2019-06-04 CN claimed
CN-109824756-A Contain 4-(benzenesulfonyl) phenylalanine derivative and the preparation method and application thereof of piperazine -2- ketone 山东大学 2019-05-31 CN claimed
CN-102558242-A Preparation of isobutyryl substituted 1,10-phenanthroline complex and application of complex serving as catalyst CHINA PETROLEUM & CHEMICAL 2012-07-11 CN claimed
CN-102532201-A Preparation of formoxyl substitutional 1, 10-phenanthroline coordination compound and application of prepared coordination compound as catalyst CHINA PETROLEUM & CHEMICAL 2012-07-04 CN claimed
CN-102485733-A Preparation of acetyl-substituted-1,10-phenanthroline complex and application of prepared complex as catalyst CHINA PETROLEUM & CHEMICAL 2012-06-06 CN claimed
CN-102485732-A Preparation of butyryl-substituted 1,10-phenanthroline complex and application of prepared complex as catalyst CHINA PETROLEUM & CHEMICAL 2012-06-06 CN claimed
CN-102060676-A Method for synthesizing trifluoromethoxybenzene HUNAN TIANCHENG PHARMACEUTICAL COMPANY LTD 2011-05-18 CN claimed
CN-100357260-C Methyl 5,5,5-trifluoro-4-(2-methyl-4-methoxyphenylimino)pentanoate and synthesis method thereof UNIV SHANGHAI (CN) 2007-12-26 CN claimed
CN-1927824-A Methyl 5,5,5-trifluoro-4-(2-methyl-4-methoxyphenylimino)pentanoate and synthesis method thereof UNIV SHANGHAI (CN) 2007-03-14 CN claimed
US-7056986-B2 ethylene monomer can be a vinyl ketone, ether, ester, halide, nitrile, aromatic, or an allyl ether; acrylic monomer can be a mono- or diacid or monoester of a diacid; a monoamine, a guanidine compound, and an aromatic diamine; improved vulcanizability, balance between processability and compression set DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2006-06-06 US claimed
CN-1069307-C Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI CHEMICALS INC (JP) 2001-08-08 CN claimed
CN-1109868-A Process for the preparation of 4-methoxy-2,2',6'-trimethyldiphenylamine MITSUI TOATSU CHEMICALS (JP) 1995-10-11 CN claimed