Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX2 | Q96LB1 | 5/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.64 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.64 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.64 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.63 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.58 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ARRB1 | P49407 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Norcodeine SCHEMBL120270 | 1.00 | MRGPRX2 (1.00) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL120271 | 1.00 | MRGPRX2 (1.00) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL29776979 | 1.00 | MRGPRX2 (1.00) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL18462800 | 1.00 | MRGPRX2 (1.00) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL16922132 | 1.00 | MRGPRX2 (1.00) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL12638889 | 1.00 | MRGPRX2 (1.00) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL4856570 | 0.99 | MRGPRX2 (0.98) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL6220787 | 0.99 | MRGPRX2 (0.98) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Norcodeine SCHEMBL7593070 | 0.98 | MRGPRX2 (0.96) | MRGPRX2MAPTOPRM1OPRK1OPRD1 | |
| Codeine SCHEMBL20703798 | 0.90 | OPRM1 (0.83) | MRGPRX2MAPTOPRM1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4201926-A1 | NOVEL INTERMEDIATE, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF | Sichuan University (CN) | 2023-06-28 | — | — | EP | disclosed |
| WO-2022127321-A1 | NOVEL INTERMEDIATE, PREPARATION METHOD FOR SAME, AND APPLICATIONS THEREOF | 四川大学 | 2022-06-23 | — | — | WO | disclosed |