Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | FAAH | O00519 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24542771 | 0.89 | ADORA2A (0.48) | PPARAALDH1A1ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL24542769 | 0.88 | ADORA2A (0.47) | PPARAALDH1A1ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL30901940 | 0.88 | ADORA2A (0.47) | PPARAALDH1A1ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL24542732 | 0.87 | EPHX2 (0.56) | PPARAALDH1A1ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL24542722 | 0.86 | PPARA (0.50) | PPARAALDH1A1ADORA2AADORA2BL3MBTL1 | |
| SCHEMBL24542730 | 0.86 | PDK1 (0.55) | PPARAALDH1A1ADORA2AADORA2BMEN1 | |
| SCHEMBL24542725 | 0.85 | PPARA (0.57) | PPARAALDH1A1ADORA2AADORA2BLMNA | |
| SCHEMBL24543063 | 0.84 | PPARA (0.54) | PPARAALDH1A1L3MBTL1MEN1LMNA | |
| SCHEMBL24542766 | 0.84 | TRPV1 (0.54) | PPARAADORA2AADORA2BMEN1LMNA | |
| SCHEMBL24543202 | 0.83 | EPHX2 (0.60) | FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4263492-B1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARM INC (US) | 2025-04-09 | — | — | EP | disclosed |
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA PHARMACEUTICALS INC. | 2024-04-25 | — | — | US | disclosed |
| EP-4263492-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | ACADIA Pharmaceuticals Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2022129933-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Pandeia Therapeutics Limited (GB) | 2022-06-23 | — | — | WO | disclosed |
| WO-2022129933-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | Pandeia Therapeutics Limited (GB) | 2022-06-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240132450-A1 | MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88 | GPR88, GPR65, GPR68 | PPARA 355/4885ALDH1A1 2127/4885ADORA2A 175/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.