SCHEMBL2454499

SCHEMBL2454499

CCNC(=S)Nc1nc(C)cs1

nearest known ligand 0.53

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 10/20 0.52
RAB9A P51151 9/20 0.52
SMN1; SMN2 Q16637 4/20 0.51
MAPT P10636 3/20 0.51
HTT P42858 3/20 0.51
KMT2A Q03164 2/20 0.51
MEN1 O00255 1/20 0.51
LMNA P02545 1/20 0.51
ALOX12 P18054 1/20 0.51
POLB P06746 2/20 0.45
ALDH1A1 P00352 2/20 0.45
HPGD P15428 2/20 0.43
KDM4E B2RXH2 2/20 0.43
TP53 P04637 1/20 0.42
GAA P10253 1/20 0.42
HSD17B10 Q99714 1/20 0.42
RCE1 Q9Y256 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8683529 0.78 NPC1 (0.45) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL6958861 0.78 NPC1 (0.45) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL8683523 0.77 NPC1 (0.47) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL8885589 0.77 ALDH1A1 (0.61) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL6838461 0.75 MAPT (0.54) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL4097866 0.72 SMN1; SMN2 (0.63) NPC1RAB9ASMN1; SMN2MAPTKMT2A
SCHEMBL8302977 0.72
SCHEMBL5373992 0.71 ALDH1A1 (0.55) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL4099160 0.71 PDE5A (0.58) NPC1RAB9ASMN1; SMN2MAPTHTT
SCHEMBL10816647 0.71 RAB9A (0.71) NPC1RAB9ASMN1; SMN2MAPTHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1980908-B1 Use of silver halide photographic material and image forming method FUJIFILM CORP (JP) 2011-09-07 EP disclosed
US-7682780-B2 Industrial X-ray photosensitive material FUJIFILM CORPORATION (JP) 2010-03-23 US disclosed
US-20100009300-A1 INDUSTRIAL X-RAY PHOTOSENSITIVE MATERIAL FUJIFILM CORPORATION (JP) 2010-01-14 US disclosed
US-7476494-B2 Silver halide photosensitive material and image-forming method using the same FUJIFILM CORPORATION (JP) 2009-01-13 US disclosed
US-7462444-B2 Image forming method for the photothermographic material FUJIFILM CORPORATION (JP) 2008-12-09 US disclosed
US-RE40603-E1 Silver halide photographic light-sensitive material FUJIFILM CORPORATION (JP) 2008-12-09 US disclosed
US-7455960-B2 Photothermographic material FUJIFILM CORPORATION (JP) 2008-11-25 US disclosed
US-7448533-B2 Medical image file management system and medical image film FUJIFILM CORPORATION (JP) 2008-11-11 US disclosed
EP-1980908-A1 Silver halide photographic material and image forming method using the same FUJIFILM Corporation (JP) 2008-10-15 EP disclosed
US-7429444-B2 Black and white photothermographic material and image forming method FUJIFILM CORPORATION (JP) 2008-09-30 US disclosed
EP-0619515-A1 Surface latent image type silver halide photographic emulsion FUJI PHOTO FILM CO., LTD. (JP) 1994-10-12 EP disclosed
EP-0613044-A2 Photographic material containing silver halide grains doped with hexa-coordinated cyano-complex FUJI PHOTO FILM CO., LTD. (JP) 1994-08-31 EP disclosed
US-5306613-A Silver halide photographic material containing selenium compound FUJI PHOTO FILM CO., LTD. (JP) 1994-04-26 US disclosed
EP-0585787-A2 Silver halide photographic material containing selenium compound FUJI PHOTO FILM CO., LTD. (JP) 1994-03-09 EP disclosed
EP-0580179-A1 Silver halide photographic material FUJI PHOTO FILM CO., LTD. (JP) 1994-01-26 EP disclosed
US-5266457-A Phosphine sulfide as sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-30 US disclosed
EP-0439069-A2 Silver halide photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-31 EP disclosed
EP-0144990-B1 PROCESS FOR PREPARING SILVER HALIDE EMULSION FUJI PHOTO FILM CO., LTD. (JP) 1990-04-25 EP disclosed
US-4665017-A GRAIN GROWTH PROMOTOR AND INHIBITOR FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed
EP-0144990-A2 Process for preparing silver halide emulsion FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed