Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 13/20 | 0.54 |
| ▸ | NPC1 | O15118 | 10/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3699546 | 0.81 | MAPT (0.64) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL3871228 | 0.81 | MAPT (0.54) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| Hydrochloric Acid SCHEMBL6989276 | 0.79 | MAPT (0.53) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| Iodide SCHEMBL8196137 | 0.77 | MAPT (0.50) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL1691061 | 0.76 | MAPT (0.68) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL10816647 | 0.76 | RAB9A (0.71) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL2454499 | 0.75 | NPC1 (0.52) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL28292387 | 0.75 | SMN1; SMN2 (0.64) | MAPTRAB9ANPC1SMN1; SMN2LMNA | |
| SCHEMBL48394 | 0.74 | MAPT (0.66) | MAPTRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL22904396 | 0.74 | MAPT (0.56) | MAPTRAB9ANPC1SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108369222-B | Opioid receptor modulators and uses thereof | 明尼苏达大学董事会 | 2021-06-04 | — | — | CN | disclosed |
| EP-3344997-B1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | UNIV MINNESOTA (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3344997-B1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | UNIV MINNESOTA (US) | 2020-11-18 | — | — | EP | disclosed |
| EP-3344997-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | Regents of the University of Minnesota (US) | 2018-07-11 | — | — | EP | disclosed |
| US-9827228-B2 | Opioid receptor modulators and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-11-28 | — | — | US | disclosed |
| US-9827228-B2 | Opioid receptor modulators and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-11-28 | — | — | US | disclosed |
| US-9827228-B2 | Opioid receptor modulators and use thereof | NATIONAL HEALTH RESEARCH INSTITUTES (TW) | 2017-11-28 | — | — | US | disclosed |
| WO-2017039778-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-03-09 | — | — | WO | disclosed |
| WO-2017039778-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | REGENTS OF THE UNIVERSITY OF MINNESOTA (US) | 2017-03-09 | — | — | WO | disclosed |
| US-20170056377-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-03-02 | — | — | US | disclosed |
| CN-1387084-A | Silver halide emulsion | FUJI PHOTO FILM CO LTD (JP) | 2002-12-25 | — | — | CN | disclosed |
| CN-1092807-C | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 2002-10-16 | — | — | CN | disclosed |
| CN-1365024-A | Silver halide photosensitive material | FUJI PHOTO FILM CO LTD (JP) | 2002-08-21 | — | — | CN | disclosed |
| CN-1347008-A | Photographic sensitive silver halide material | FUJI PHOTO FILM CO LTD (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1340739-A | Silver halide photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2002-03-20 | — | — | CN | disclosed |
| CN-1329274-A | Silver halide photographic photosensitive material | FUJI PHOTO FILM CO LTD (JP) | 2002-01-02 | — | — | CN | disclosed |
| CN-1301982-A | Silver halide photographic emulsion and photosensitive material using said emulsion | FUJI PHOTO FILM CO LTD (JP) | 2001-07-04 | — | — | CN | disclosed |
| CN-1187635-A | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1998-07-15 | — | — | CN | disclosed |
| CN-1148185-A | Silver halide photographic material | FUJI PHOTO FILM CO LTD (JP) | 1997-04-23 | — | — | CN | disclosed |
| CN-1069882-A | The Compounds and methods for that suppresses HIV and correlated virus | MEDIVIR AB (CH) | 1993-03-17 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170056377-A1 | OPIOID RECEPTOR MODULATORS AND USE THEREOF | OPRM1, OPRK1, OPRL1 | MAPT 2397/4885RAB9A 2256/4885NPC1 2226/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.