Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.32 |
| ▸ | DUT | P33316 | 1/20 | 0.32 |
| ▸ | PLAT | P00750 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BTN3A1 | O00481 | 1/20 | 0.31 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.31 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25721246 | 0.87 | CYP3A4 (0.45) | MEN1KMT2ACYP3A4CYP2C9DUT | |
| SCHEMBL25723712 | 0.87 | CYP3A4 (0.45) | MEN1KMT2ACYP3A4CYP2C9DUT | |
| SCHEMBL25727013 | 0.76 | CYP3A4 (0.41) | CYP3A4CYP2C9DUTP2RY2P2RY6 | |
| SCHEMBL25714956 | 0.76 | CYP3A4 (0.45) | CYP3A4CYP2C9DUTP2RY2P2RY6 | |
| SCHEMBL25724478 | 0.76 | CYP3A4 (0.45) | CYP3A4CYP2C9DUTP2RY2P2RY6 | |
| SCHEMBL25714223 | 0.74 | DUT (0.49) | MEN1KMT2ACYP3A4CYP2C9TYMS | |
| SCHEMBL13875655 | 0.73 | TK1 (0.41) | TYMS | |
| SCHEMBL24547497 | 0.70 | CYP3A4 (0.50) | MEN1KMT2AUSP2POLBCYP3A4 | |
| SCHEMBL29637585 | 0.70 | CYP3A4 (0.50) | MEN1KMT2AUSP2POLBCYP3A4 | |
| SCHEMBL24547483 | 0.70 | CYP3A4 (0.50) | MEN1KMT2AUSP2POLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133323-A1 | 6-AZA-NUCLEOSIDE PRODRUGS AS ANTIVIRAL AGENTS FOR TREATING VIRUS INFECTIONS | SOUTHERN RESEARCH INSTITUTE (US) | 2022-06-23 | — | — | WO | disclosed |