Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 1/20 | 0.31 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24541093 | 1.00 | P2RX3 (0.31) | P2RX3P2RX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24541092 | 1.00 | P2RX3 (0.31) | P2RX3P2RX2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL24540925 | 0.80 | TRPV4 (0.38) | SLC6A3 | |
| SCHEMBL31043203 | 0.80 | TRPV4 (0.38) | SLC6A3 | |
| SCHEMBL24547910 | 0.80 | TRPV4 (0.38) | SLC6A3 | |
| SCHEMBL24540924 | 0.80 | TRPV4 (0.38) | SLC6A3 | |
| SCHEMBL24540773 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL24540771 | 0.79 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL24541226 | 0.79 | NPSR1 (0.35) | — | |
| SCHEMBL24541228 | 0.79 | NPSR1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022132914-A1 | PRMTS INHIBITORS | AMGEN INC. (US) | 2022-06-23 | — | — | WO | disclosed |