Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CTSZ | Q9UBR2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2992695 | 0.78 | FDPS (0.50) | ALDH1A1KDM4EFDPSLMNACTSZ | |
| SCHEMBL8220401 | 0.78 | FDPS (0.53) | ALDH1A1KDM4EFDPSCTSZNPSR1 | |
| SCHEMBL4290130 | 0.76 | KMT2A (0.53) | ALDH1A1KDM4EHSD17B10FDPSCTSZ | |
| SCHEMBL6180509 | 0.75 | FDPS (0.50) | ALDH1A1SMN1; SMN2HSD17B10FDPSCTSZ | |
| SCHEMBL8429865 | 0.74 | FDPS (0.53) | ALDH1A1HPGDSMN1; SMN2FDPSCTSZ | |
| SCHEMBL8267936 | 0.74 | KMT2A (0.51) | ALDH1A1HPGDSMN1; SMN2KDM4EHSD17B10 | |
| SCHEMBL11839258 | 0.72 | ALDH1A1 (0.58) | ALDH1A1ATMHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL5343833 | 0.72 | — | — | |
| SCHEMBL11341707 | 0.71 | TXN (0.41) | ALDH1A1HPGDSMN1; SMN2HSD17B10FDPS | |
| Hydrochloric Acid SCHEMBL9805610 | 0.71 | CTSZ (0.48) | ALDH1A1HPGDKDM4EHSD17B10FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022129256-A1 | SELECTIVE HDAC6 INHIBITOR | ROYAL COLLEGE OF SURGEONS IN IRELAND (IE) | 2022-06-23 | — | — | WO | disclosed |