Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053434 | 0.92 | AR (0.37) | DYRK1ANPC1RAB9AALDH1A1NAMPT | |
| SCHEMBL1761182 | 0.84 | TSHR (0.39) | DYRK1ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL25816117 | 0.84 | PTGES (0.35) | DYRK1ANPC1RAB9AALDH1A1MEN1 | |
| SCHEMBL29122661 | 0.78 | DYRK1A (0.38) | DYRK1ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL21143326 | 0.75 | EGFR (0.39) | DYRK1ANPC1RAB9APTPN1ALDH1A1 | |
| SCHEMBL30509819 | 0.75 | EGFR (0.39) | DYRK1ANPC1RAB9APTPN1ALDH1A1 | |
| SCHEMBL23680455 | 0.75 | ALDH1A1 (0.51) | KDM4EALDH1A1MEN1KMT2ASCN8A | |
| SCHEMBL1761232 | 0.74 | MAOB (0.50) | NPC1RAB9AKDM4ETSHR | |
| SCHEMBL27990728 | 0.74 | MAP3K7 (0.40) | DYRK1ANPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6389982 | 0.73 | SSTR2 (0.39) | DYRK1ANPC1RAB9AAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022133037-A1 | MACROCYCLES AND THEIR USE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2022-06-23 | — | — | WO | disclosed |