Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24553670 | 0.92 | DYRK1A (0.35) | ARMEN1KMT2AALDH1A1DYRK1A | |
| SCHEMBL1761182 | 0.82 | TSHR (0.39) | ARMEN1KMT2AALDH1A1DYRK1A | |
| SCHEMBL25816117 | 0.82 | PTGES (0.35) | MEN1KMT2AALDH1A1DYRK1ANPC1 | |
| SCHEMBL9957027 | 0.82 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1RECQLMCHR1 | |
| SCHEMBL20621276 | 0.80 | TSHR (0.46) | ARALDH1A1RECQLESR2 | |
| SCHEMBL29122661 | 0.79 | DYRK1A (0.38) | ARMEN1KMT2AALDH1A1DYRK1A | |
| SCHEMBL21143326 | 0.77 | EGFR (0.39) | ALDH1A1DYRK1ANPC1RAB9ANAMPT | |
| SCHEMBL30509819 | 0.77 | EGFR (0.39) | ALDH1A1DYRK1ANPC1RAB9ANAMPT | |
| SCHEMBL22096797 | 0.76 | LMNA (0.39) | ARKMT2AALDH1A1RECQLESR2 | |
| SCHEMBL19768964 | 0.76 | GABRA1 (0.40) | ARALDH1A1RECQLNAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377847-A | Kinase inhibitors | CHIESI FARM SPA | 2016-03-02 | — | — | CN | disclosed |