SCHEMBL24554274

SCHEMBL24554274

CN(C)CCC(=O)N1CCn2nc(-c3ccc(F)cc3)c(B3OC(C)(C)C(C)(C)O3)c2C1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CSNK1E P49674 10/20 0.41
CSNK1D P48730 7/20 0.41
ACKR3 P25106 1/20 0.35
DPP4 P27487 2/20 0.34
KCNK3 O14649 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
LPL P06858 1/20 0.33
LIPG Q9Y5X9 1/20 0.33
ENPP2 Q13822 1/20 0.33
GRM5 P41594 1/20 0.33
BTK Q06187 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24547960 0.85 CSNK1E (0.46) CSNK1ECSNK1DKCNK3LPLLIPG
SCHEMBL24553872 0.83 GRM5 (0.45) CSNK1ECSNK1DKCNK3GRM5
SCHEMBL29683344 0.81 CSNK1E (0.46) CSNK1ECSNK1DACKR3DPP4KCNK3
SCHEMBL24548256 0.77 LPL (0.42) CSNK1ECSNK1DLPLLIPG
SCHEMBL24554423 0.77 L3MBTL1 (0.43) CSNK1ECSNK1DL3MBTL1GRM5
SCHEMBL24553820 0.76 CSNK1E (0.41) CSNK1ECSNK1DACKR3DPP4GRM5
SCHEMBL24553855 0.75 KCNK3 (0.42) CSNK1ECSNK1DKCNK3LPLLIPG
SCHEMBL24547936 0.75 CSNK1E (0.44) CSNK1ECSNK1DLPLLIPG
SCHEMBL29683101 0.74 CSNK1E (0.40) CSNK1ECSNK1DACKR3DPP4
SCHEMBL14844993 0.73 THRB (0.46) CSNK1ECSNK1DLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250276972-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS GRITSCIENCE BIOPHARMACEUTICALS CO LTD (CN) 2025-09-04 US disclosed
WO-2022127756-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2022-06-23 WO disclosed
WO-2022127756-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS Gritscience Biopharmaceuticals Co., Ltd. (CN) 2022-06-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250276972-A1 COMPOUNDS AS CASEIN KINASE INHIBITORS PACSIN2, CSNK1A1, CSNK1G3 CSNK1E 4/4885CSNK1D 12/4885ACKR3 3824/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.