SCHEMBL24555199

SCHEMBL24555199

CC(C)(C)NCCNC(=O)c1cccc(OCC(N)OC(C)(C)C)c1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TP53BP1 Q12888 4/20 0.47
▸ F10 P00742 2/20 0.42
▸ ALDH1A1 P00352 2/20 0.42
▸ DGAT1 O75907 1/20 0.41
▸ NR1H4 Q96RI1 1/20 0.41
▸ LMNA P02545 1/20 0.41
▸ KMT2A Q03164 1/20 0.41
▸ GAA P10253 1/20 0.39
▸ MAPT P10636 1/20 0.39
▸ HDAC3 O15379 1/20 0.39
▸ KAT6A Q92794 1/20 0.39
▸ POLB P06746 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24554840 0.89 KMT2A (0.42) TP53BP1F10ALDH1A1DGAT1NR1H4
SCHEMBL23366317 0.88 TP53BP1 (0.53) TP53BP1F10ALDH1A1DGAT1NR1H4
SCHEMBL22545191 0.79 TP53BP1 (0.52) TP53BP1F10ALDH1A1DGAT1LMNA
SCHEMBL23366318 0.78 TP53BP1 (0.47) TP53BP1ALDH1A1DGAT1NR1H4LMNA
SCHEMBL22545083 0.77 KDM4E (0.38) TP53BP1F10ALDH1A1DGAT1LMNA
SCHEMBL18359680 0.74 SPHK2 (0.49) F10ALDH1A1NR1H4LMNAKMT2A
SCHEMBL19120376 0.72 KMT2A (0.38) F10ALDH1A1DGAT1KMT2AGAA
SCHEMBL21972887 0.72 NPC1 (0.61) TP53BP1ALDH1A1LMNAKMT2AGAA
SCHEMBL24023148 0.72 NR1H4 (0.59) ALDH1A1NR1H4LMNAKMT2AGAA
SCHEMBL22349844 0.71 TP53BP1 (0.85) TP53BP1ALDH1A1LMNAKMT2AGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370920-B2 Fluorescent dyes and their uses as biomarkers ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-28 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11370920-B2 Fluorescent dyes and their uses as biomarkers FBL, HNRNPF, EWSR1 TP53BP1 287/4885F10 3188/4885ALDH1A1 895/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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