Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.59 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | USP2 | O75604 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | FABP1 | P07148 | 1/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22327061 | 0.88 | NR1H4 (0.58) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL22327391 | 0.86 | NR1H4 (0.56) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL24971589 | 0.86 | NR1H4 (0.56) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL22327159 | 0.86 | MAPT (0.55) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL26168405 | 0.85 | SMN1; SMN2 (0.59) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL24002288 | 0.81 | NR1H4 (0.53) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL23957821 | 0.80 | NR1H4 (0.41) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL22219742 | 0.80 | NR1H4 (0.52) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL24002403 | 0.80 | KAT6A (0.41) | NR1H4KAT6AKMT2AALDH1A1HTT | |
| SCHEMBL16108766 | 0.78 | NR1H4 (0.60) | NR1H4KAT6AKMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-08-17 | — | — | US | disclosed |
| US-20230160001-A1 | NUCLEOTIDE CLEAVABLE LINKERS WITH RIGID SPACERS AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-05-25 | — | — | US | disclosed |
| US-20230002436-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | FIRST-CITIZENS BANK & TRUST COMPANY | 2023-01-05 | — | — | US | disclosed |
| US-11174281-B1 | Modified nucleotides and uses thereof | Singular Genomics Systems, Inc. (US) | 2021-11-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230002436-A1 | MODIFIED NUCLEOTIDES AND USES THEREOF | NUDT1, RNMT, ADAR | NR1H4 4394/4885KAT6A 2028/4885KMT2A 1548/4885 |
| US-20230257414-A1 | NUCLEOTIDE ANALOGUES | ITPA, POLB, NUDT1 | NR1H4 3934/4885KAT6A 2123/4885KMT2A 1334/4885 |
| US-11174281-B1 | Modified nucleotides and uses thereof | NUDT1, RNMT, ADAR | NR1H4 4394/4885KAT6A 2028/4885KMT2A 1548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.