Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24555199 | 0.89 | TP53BP1 (0.47) | KMT2AMAPTGAAALDH1A1F10 | |
| SCHEMBL23366317 | 0.77 | TP53BP1 (0.53) | KMT2AMAPTGAAALDH1A1F10 | |
| SCHEMBL24554839 | 0.73 | ALDH1A1 (0.37) | KMT2AMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL18359680 | 0.73 | SPHK2 (0.49) | KMT2AMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL22894138 | 0.71 | ALDH1A1 (0.37) | KMT2AMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL19120376 | 0.70 | KMT2A (0.38) | KMT2AMAPTGAAALDH1A1F10 | |
| SCHEMBL23366318 | 0.70 | TP53BP1 (0.47) | KMT2AMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL10294705 | 0.69 | L3MBTL1 (0.60) | KMT2AMAPTGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL22545191 | 0.69 | TP53BP1 (0.52) | KMT2AMAPTGAAALDH1A1F10 | |
| SCHEMBL25571882 | 0.69 | F10 (0.43) | KMT2AMAPTGAAALDH1A1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11371078-B2 | Coumarin compounds and their uses as fluorescent labels | ILLUMINA CAMBRIDGE LIMITED (GB) | 2022-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11371078-B2 | Coumarin compounds and their uses as fluorescent labels | FBL, PHAX, DUT | KMT2A 3628/4885MAPT 2438/4885GAA 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.