Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pantothenic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.63 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.63 |
| ▸ | VNN1 | O95497 | 13/20 | 0.55 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pantothenic Acid SCHEMBL2455674 | 1.00 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL30553124 | 1.00 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL29355079 | 1.00 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL34428 | 1.00 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL34427 | 1.00 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL7084077 | 0.98 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL8044584 | 0.98 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL11750098 | 0.98 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL11750103 | 0.98 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL7084078 | 0.98 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113974011-A | Feed additive for relieving heat stress of broiler chickens | 中国农业科学院北京畜牧兽医研究所 | 2022-01-28 | — | — | CN | claimed |
| CN-113974011-A | Feed additive for relieving heat stress of broiler chickens | 中国农业科学院北京畜牧兽医研究所 | 2022-01-28 | — | — | CN | disclosed |
| US-20200077689-A1 | DIETARY SUPPLEMENT FORMULATIONS | LIFE KITCHEN LLC (US) | 2020-03-12 | — | — | US | disclosed |
| US-8507015-B2 | Composition for countering the effects of alcohol consumption | Lquid Innovations, LLC (US) | 2013-08-13 | — | — | US | disclosed |
| WO-2011116480-A1 | FOOD COMPOSITION COMPRISING GERMINATED SEEDS OR GRAINS | NORMERICA INC. (CA) | 2011-09-29 | — | — | WO | disclosed |
| US-20110217392-A1 | COMPOSITION FOR COUNTERING THE EFFECTS OF ALCOHOL CONSUMPTION | LIQUID INNOVATIONS, LLC (US) | 2011-09-08 | — | — | US | disclosed |
| US-20100330006-A1 | Antimicrobial lotion compositions | LABORATORY SKIN CARE, INC. | 2010-12-30 | — | — | US | disclosed |
| US-7771753-B2 | Topical formulations comprising ceramic hydroxyapatite particles | LABORATORY SKIN CARE, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-7655250-B2 | Topical formulations comprising ceramic hydroxyapatite particles | LABORATORY SKIN CARE, INC. (US) | 2010-02-02 | — | — | US | disclosed |
| US-20090104133-A1 | Methods of Moisturizing the Skin and Killing Microorganisms Thereon | MANSOURI ZAHRA | 2009-04-23 | — | — | US | disclosed |
| WO-2007038524-A2 | COCRYSTALLIZATION METHODS | SSCI, INC. (US) | 2007-04-05 | — | — | WO | disclosed |
| US-20060193879-A1 | Topical formulations comprising ceramic hydroxyapatite particles | LABORATORY SKIN CARE, INC. | 2006-08-31 | — | — | US | disclosed |
| US-6579516-B1 | Methods of delivering materials into the skin, and compositions used therein | LABORATORY SKIN CARE, INC. | 2003-06-17 | — | — | US | disclosed |
| US-20030077235-A1 | Topical formulations comprising ceramic hydroxyapatite particles | LABORATORY SKIN CARE, INC. | 2003-04-24 | — | — | US | disclosed |
| US-20010006680-A1 | SKIN CARE MOISTURIZERS AND CLEANSERS | LABORATORY SKIN CARE, INC. | 2001-07-05 | — | — | US | disclosed |
| US-6099849-A | Skin care moisturizers and cleansers | MANSOURI, ZAHRA | 2000-08-08 | — | — | US | disclosed |
| US-5122369-A | Nutrient composition for preventing hair loss | HARMONY HEALTH PRODUCTS, INC. (US) | 1992-06-16 | — | — | US | disclosed |