Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Pantothenic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.61 |
| ▸ | VNN1 | O95497 | 13/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pantothenic Acid SCHEMBL2455674 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL2455672 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL29355079 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL34428 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL34427 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL30553124 | 0.98 | PTGS1 (0.63) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL7084077 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL11750098 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL11750103 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 | |
| Pantothenic Acid SCHEMBL7084078 | 0.97 | PTGS1 (0.61) | PTGS1KCNH2VNN1BBOX1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6039978-A | HOMOGENOUS FREE-FLOWING POWDER FOOD ENHANCING AGENT WITH CALCIUM, MAGNESIUM PHOSPHOROUS USING DICALCIUM PHOSPHATE, CALCIUM CITRATE AND MAGNESIUM PHOSPHATE | CAMPBELL SOUP COMPANY (US) | 2000-03-21 | — | — | US | disclosed |
| US-6039989-A | PREPACKAGED THERAPUTIC MEALS FOR DIETS | CAMPBELL SOUP COMPANY (US) | 2000-03-21 | — | — | US | disclosed |
| US-5994295-A | ADMINISTERING PREPACKAGED MEALS | CAMPBELL SOUP COMPANY (US) | 1999-11-30 | — | — | US | disclosed |
| US-5977059-A | THERAPY FOR DIET RESPONSIVE CONDITIONS | CAMPBELL SOUP COMPANY (US) | 1999-11-02 | — | — | US | disclosed |