SCHEMBL2455845

SCHEMBL2455845

C=C(C)CCC(P(=O)(O)O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.39

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
BTN3A1 O00481 1/20 0.39
FDPS P14324 14/20 0.34
GGPS1 O95749 7/20 0.31
LMNA P02545 2/20 0.31
ADRB3 P13945 1/20 0.30
PDE4D Q08499 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6898336 0.77 BTN3A1 (0.37) BTN3A1FDPS
SCHEMBL9802369 0.76 FDPS (0.41) BTN3A1FDPSLMNAADRB3PDE4D
SCHEMBL2463935 0.75 BTN3A1 (0.33) BTN3A1FDPSLMNA
SCHEMBL19211961 0.69 FDPS (0.59) FDPSGGPS1LMNA
Phosphoric Acid SCHEMBL5963882 0.67 BTN3A1 (0.43) BTN3A1FDPS
SCHEMBL2454026 0.67
SCHEMBL19211969 0.66 GRM4 (0.52) FDPSLMNAADRB3PDE4DPDE3A
SCHEMBL791153 0.66
SCHEMBL4822827 0.65
SCHEMBL9413479 0.64

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity MONTERO JEAN-LOUIS 2006-10-26 US claimed
JP-2005511748-A 2005-04-28 JP claimed
EP-1453840-A1 PHOSPHONATES USEFUL AS MODULATORS OF T-GAMMA-9-DELTA-2 LYMPHOCYTE ACTIVITY Laboratoire Mayoly Spindler (FR) 2004-09-08 EP claimed
WO-2003050128-A1 PHOSPHONATES USEFUL AS MODULATORS OF T $G(G)9$G(D)2 LYMPHOCYTE ACTIVITY LABORATOIRE MAYOLY SPINDLER (FR) 2003-06-19 WO claimed
US-8017596-B2 Phosphonates useful as modulators of T-γ-9-δ-2 activity INNATE PHARMA, S.A. (FR) 2011-09-13 US disclosed
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject INNATE PHARMA, S.A. (FR) 2010-10-07 US disclosed
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity LABORATOIRES MAYOLY SPINDLER (FR) 2010-08-12 US disclosed
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer INNATE PHARMA S.A. (FR) 2010-07-29 US disclosed
WO-2010049438-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS FOR THE TREATMENT OF DISEASES INNATE PHARMA (FR) 2010-05-06 WO disclosed
EP-1569656-B1 PHOSPHOANTIGENS FOR REGULATING AN IMMUNE RESPONSE INNATE PHARMA (FR) 2010-03-03 EP disclosed
EP-2150258-A2 IMPROVED METHODS OF USING PHOSPHOANTIGENS TOGETHER WITH INTERLEUKIN-2 FOR THE TREATMENT OF CANCER Innate Pharma S.A. (FR) 2010-02-10 EP disclosed
US-20100029674-A1 Methods of Using Phosphoantigen for the Treatment of Cancer INNATE PHARMA, S.A. (FR) 2010-02-04 US disclosed
WO-2007039635-A2 PHOSPHOANTIGEN SALTS OF ORGANIC BASES AND METHODS FOR THEIR CRYSTALLIZATION INNATE PHARMA (FR) 2007-04-12 WO disclosed
EP-1720567-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA Innate Pharma (FR) 2006-11-15 EP disclosed
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity MONTERO JEAN-LOUIS 2006-10-26 US disclosed
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject INNATE PHARMA, S.A.S. (FR) 2006-08-31 US disclosed
WO-2006067635-A2 USE OF Ϝδ T LYMPHOCYTE ACTIVATORS AS VACCINE ADJUVANT INNATE PHARMA S.A. (FR) 2006-06-29 WO disclosed
WO-2005077411-A2 COMPOSITION AND METHOD FOR THE TREATMENT OF CARCINOMA INNATE PHARMA (FR) 2005-08-25 WO disclosed
EP-1453840-A1 PHOSPHONATES USEFUL AS MODULATORS OF T-GAMMA-9-DELTA-2 LYMPHOCYTE ACTIVITY Laboratoire Mayoly Spindler (FR) 2004-09-08 EP disclosed
WO-2003050128-A1 PHOSPHONATES USEFUL AS MODULATORS OF T $G(G)9$G(D)2 LYMPHOCYTE ACTIVITY LABORATOIRE MAYOLY SPINDLER (FR) 2003-06-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100254940-A1 Compositions and Methods for Regulating an Immune Response in a Subject IFNG, IL2, ICOS BTN3A1 288/4885FDPS 3637/4885GGPS1 1850/4885
US-20100204184-A1 Phosphonates useful as modulators of T-gamma-9-delta-2 activity CD4, PRKCD, PRKCZ BTN3A1 417/4885FDPS 2881/4885GGPS1 646/4885
US-20100029674-A1 Methods of Using Phosphoantigen for the Treatment of Cancer CD4, CD74, TP53 BTN3A1 536/4885FDPS 4547/4885GGPS1 3039/4885
US-20100189681-A1 Methods of Using Phosphoantigens Together with Interleukin-2 for the Treatment of Cancer IL2, IL2RA, CD4 BTN3A1 539/4885FDPS 3228/4885GGPS1 1645/4885
US-20060194755-A1 Compositions and methods for regulating an immune response in a subject IFNG, IL2, ICOS BTN3A1 279/4885FDPS 3639/4885GGPS1 1944/4885
US-20060241087-A1 Phosphonates useful as modulators of t $g(g)9$g(d)2 lymphocyte activity CD4, GNG2, PLCG2 BTN3A1 797/4885FDPS 2441/4885GGPS1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.