Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.38 |
| ▸ | TAS1R2 | Q8TE23 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24568621 | 0.83 | MLYCD (0.35) | TAS1R3TAS1R1TAS1R2POLB | |
| SCHEMBL24567754 | 0.79 | POLB (0.45) | TAS1R3TAS1R1TAS1R2POLBTRPA1 | |
| SCHEMBL18793674 | 0.79 | POLB (0.45) | TAS1R3TAS1R1TAS1R2POLBTRPA1 | |
| SCHEMBL24567759 | 0.77 | — | — | |
| SCHEMBL2820334 | 0.72 | TAS1R3 (0.46) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL13829831 | 0.72 | MAPT (0.35) | — | |
| SCHEMBL13401126 | 0.70 | MAPT (0.37) | POLB | |
| SCHEMBL24785341 | 0.68 | TAS1R3 (0.41) | TAS1R3TAS1R1TAS1R2 | |
| SCHEMBL22298130 | 0.67 | CA2 (0.42) | TAS1R3TAS1R1TAS1R2POLB | |
| SCHEMBL24785343 | 0.67 | CA2 (0.42) | TAS1R3TAS1R1TAS1R2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |