Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | FDPS | P14324 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6442872 | 1.00 | HCAR3 (0.50) | HCAR3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9847026 | 0.86 | KDM4E (0.49) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL21018364 | 0.85 | TLR8 (0.47) | HCAR3MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL6439928 | 0.85 | TLR8 (0.47) | HCAR3MEN1KMT2AL3MBTL1KDM4E | |
| SCHEMBL4969096 | 0.83 | FDPS (0.50) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL7465452 | 0.83 | FDPS (0.50) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL19581191 | 0.83 | KDM4E (0.46) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL4969090 | 0.83 | FDPS (0.50) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL1831586 | 0.83 | KDM4E (0.46) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL19090765 | 0.81 | POLB (0.42) | MEN1KMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |