Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | FDPS | P14324 | 1/20 | 0.46 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | FABP1 | P07148 | 1/20 | 0.42 |
| ▸ | FABP6 | P51161 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16041382 | 0.86 | KDM4E (0.44) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL29888494 | 0.86 | KDM4E (0.44) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL24568583 | 0.83 | HCAR3 (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL6442872 | 0.83 | HCAR3 (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL19581191 | 0.81 | KDM4E (0.46) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL4969090 | 0.81 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL7465452 | 0.81 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL4969096 | 0.81 | FDPS (0.50) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL6439928 | 0.80 | TLR8 (0.47) | KDM4EHTTNPSR1L3MBTL1FDPS | |
| SCHEMBL21018364 | 0.80 | TLR8 (0.47) | KDM4EHTTNPSR1L3MBTL1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1753457-B1 | CATIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND USES THEREOF | YEDA RES & DEV (IL) | 2016-08-10 | — | — | EP | disclosed |
| EP-2322173-B1 | Cationic bacteriochlorophyll derivatives and uses thereof | YEDA RES & DEV (IL) | 2016-08-10 | — | — | EP | disclosed |
| US-8207154-B2 | Palladium 31-oxo-15- methoxycarbonylmethyl- Rhodobacteriochlorin-131-(2-N3- trimethylammoniumethyl)amide acetate (salt); bacteriochlorophylls free of carbamate group; as photosensitizer for thermodynamic therapy and diagnosis; cancer, age related macular degeneration; killing viruses and bacteria | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2012-06-26 | — | — | US | disclosed |
| EP-2322173-A1 | Cationic bacteriochlorophyll derivatives and uses thereof | YEDA RESEARCH AND DEVELOPMENT CO., LTD. (IL) | 2011-05-18 | — | — | EP | disclosed |
| US-20080076748-A1 | Catatonic Bacteriochlorophyll Derivatives | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2008-03-27 | — | — | US | disclosed |
| EP-1753457-A2 | CATIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO., Ltd. (IL) | 2007-02-21 | — | — | EP | disclosed |
| WO-2005120573-A2 | CATIONIC BACTERIOCHLOROPHYLL DERIVATIVES AND USES THEREOF | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-12-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080076748-A1 | Catatonic Bacteriochlorophyll Derivatives | CAT, PPOX, SCLY | KDM4E 4346/4885HTT 3352/4885NPSR1 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.