Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PDE6D | O43924 | 1/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22507395 | 0.93 | ESR1 (0.46) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL22522519 | 0.93 | ESR1 (0.46) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL22522249 | 0.90 | KDM4E (0.47) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL22507218 | 0.88 | ESR1 (0.41) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL22513650 | 0.88 | ESR1 (0.41) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL15940161 | 0.87 | RAB9A (0.40) | ESR1ESR2PTGS2KDM4EHSD17B10 | |
| SCHEMBL22522527 | 0.87 | ESR1 (0.40) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL22507194 | 0.87 | ESR1 (0.40) | ESR1ESR2PTGS2TSHRKDM4E | |
| SCHEMBL15940311 | 0.86 | NLRP3 (0.40) | ESR1ESR2PTGS2ALDH1A1GAA | |
| SCHEMBL13299528 | 0.86 | NLRP3 (0.52) | ESR1ESR2PTGS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2362889-B1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORP (US) | 2018-12-26 | — | — | EP | disclosed |
| US-9257658-B2 | Method of making organic electroluminescent materials | UNIVERSAL DISPLAY CORPORATION (US) | 2016-02-09 | — | — | US | disclosed |
| EP-2957566-A1 | ORGANIC LIGHT EMITTING DEVICE, HETEROLEPTIC IRIDIUM COMPLEXES AND METHOD OF PRODUCING 2-PHENYL BENZIMIDAZOLE DERIVATIVES | Universal Display Corporation (US) | 2015-12-23 | — | — | EP | disclosed |
| EP-2710020-B1 | PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY | UNIVERSAL DISPLAY CORP (US) | 2015-06-24 | — | — | EP | disclosed |
| US-20140303370-A1 | METHOD OF MAKING ORGANIC ELECTROLUMINESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION | 2014-10-09 | — | — | US | disclosed |
| US-20140303370-A1 | METHOD OF MAKING ORGANIC ELECTROLUMINESCENT MATERIALS | UNIVERSAL DISPLAY CORPORATION | 2014-10-09 | — | — | US | disclosed |
| US-8795850-B2 | Phosphorescent heteroleptic phenylbenzimidazole dopants and new synthetic methodology | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-05 | — | — | US | disclosed |
| US-8795850-B2 | Phosphorescent heteroleptic phenylbenzimidazole dopants and new synthetic methodology | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-05 | — | — | US | disclosed |
| US-20130341599-A1 | Phosphorescent Emitters | UNIVERSAL DISPLAY CORPORATION (US) | 2013-12-26 | — | — | US | disclosed |
| US-8367223-B2 | Heteroleptic phosphorescent emitters | UNIVERSAL DISPLAY CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367223-B2 | Heteroleptic phosphorescent emitters | UNIVERSAL DISPLAY CORPORATION (US) | 2013-02-05 | — | — | US | disclosed |
| US-20120292601-A1 | PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY | UNIVERSAL DISPLAY CORPORATION (US) | 2012-11-22 | — | — | US | disclosed |
| WO-2012158851-A1 | PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY | UNIVERSAL DISPLAY CORPORATION (US) | 2012-11-22 | — | — | WO | disclosed |
| EP-2362889-A1 | PHOSPHORESCENT EMITTERS | Universal Display Corporation (US) | 2011-09-07 | — | — | EP | disclosed |
| US-20100141127-A1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100141127-A1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| US-20100141127-A1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2010-06-10 | — | — | US | disclosed |
| WO-2010056669-A1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
| WO-2010056669-A1 | PHOSPHORESCENT EMITTERS | UNIVERSAL DISPLAY CORPORATION (US) | 2010-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100141127-A1 | PHOSPHORESCENT EMITTERS | PAICS, TYMP, NUDT1 | ESR1 1399/4885ESR2 1078/4885PTGS2 2873/4885 |
| US-20120292601-A1 | PHOSPHORESCENT HETEROLEPTIC PHENYLBENZIMIDAZOLE DOPANTS AND NEW SYNTHETIC METHODOLOGY | POF1B, OCIAD1, OCIAD2 | ESR1 3504/4885ESR2 3483/4885PTGS2 3489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.