Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15940161 | 0.91 | RAB9A (0.40) | HDAC1HDAC8HDAC6ESR1ESR2 | |
| SCHEMBL15946180 | 0.90 | NLRP3 (0.39) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL13299528 | 0.90 | NLRP3 (0.52) | NLRP3SIRT2SIRT1ESR1ESR2 | |
| SCHEMBL15940200 | 0.87 | ALDH1A1 (0.43) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL2456887 | 0.86 | ESR1 (0.51) | ESR1ESR2ALDH1A1GAAPTGS2 | |
| SCHEMBL15946181 | 0.85 | NLRP3 (0.37) | NLRP3HDAC1HDAC8HDAC6SIRT2 | |
| SCHEMBL22507395 | 0.83 | ESR1 (0.46) | ESR1ESR2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL22522519 | 0.83 | ESR1 (0.46) | ESR1ESR2ALDH1A1GAAL3MBTL1 | |
| SCHEMBL15940168 | 0.82 | ALDH1A1 (0.36) | NLRP3HDAC1HDAC8HDAC6ESR1 | |
| SCHEMBL22522249 | 0.80 | KDM4E (0.47) | ESR1ESR2ALDH1A1GAAPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10400163-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-09-03 | — | — | US | disclosed |
| US-10400163-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-09-03 | — | — | US | disclosed |
| US-9108986-B2 | Method for producing optically active tetrahydroquinolines | HAMARI CHEMICALS, LTD. (JP) | 2015-08-18 | — | — | US | disclosed |
| US-20140225069-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140225069-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-14 | — | — | US | disclosed |
| US-20140228572-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE TETRAHYDROQUINOLINES | HAMARI CHEMICALS, LTD. (JP) | 2014-08-14 | — | — | US | disclosed |
| US-20140225069-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2014-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10400163-B2 | Organic electroluminescent materials and devices | INTS9, SRSF9, PRMT9 | NLRP3 2980/4885HDAC1 1430/4885HDAC8 3716/4885 |
| US-20140228572-A1 | METHOD FOR PRODUCING OPTICALLY ACTIVE TETRAHYDROQUINOLINES | QDPR, IDH3B, IDH3A | NLRP3 2221/4885HDAC1 297/4885HDAC8 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.