Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | ADH1A | P07327 | 2/20 | 0.40 |
| ▸ | ADH1B | P00325 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24429228 | 0.95 | ADH1A (0.47) | ADH1CADH1AADH1BMEN1KMT2A | |
| SCHEMBL6205344 | 0.95 | ADH1A (0.47) | ADH1CADH1AADH1BMEN1KMT2A | |
| SCHEMBL15461406 | 0.92 | ADH1B (0.32) | ADH1CADH1AADH1BALDH1A1 | |
| SCHEMBL24391650 | 0.78 | ADH1B (0.39) | ADH1CADH1AADH1B | |
| SCHEMBL24429231 | 0.78 | ADH1B (0.39) | ADH1CADH1AADH1B | |
| SCHEMBL7511009 | 0.78 | MEN1 (0.38) | ADH1CADH1AADH1BMEN1KMT2A | |
| SCHEMBL8299579 | 0.78 | ADH1C (0.40) | ADH1CADH1AADH1BMEN1KMT2A | |
| SCHEMBL21789769 | 0.76 | — | — | |
| SCHEMBL24391652 | 0.76 | ADH1A (0.42) | ADH1CADH1AADH1BMEN1KMT2A | |
| SCHEMBL23872686 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022140390-A1 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |
| WO-2022140428-A2 | INHIBITORS OF PEPTIDYLARGININE DEIMINASES | GILEAD SCIENCES, INC. (US) | 2022-06-30 | — | — | WO | disclosed |