Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 4/20 | 0.47 |
| ▸ | ADH1C | P00326 | 3/20 | 0.47 |
| ▸ | ADH1B | P00325 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | PER2 | O15055 | 1/20 | 0.33 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.33 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24429228 | 1.00 | ADH1A (0.47) | ADH1AADH1CADH1BMEN1KMT2A | |
| SCHEMBL24568892 | 0.95 | ADH1C (0.40) | ADH1AADH1CADH1BMEN1KMT2A | |
| SCHEMBL15461406 | 0.88 | ADH1B (0.32) | ADH1AADH1CADH1BALDH1A1 | |
| SCHEMBL8299579 | 0.82 | ADH1C (0.40) | ADH1AADH1CADH1BMEN1KMT2A | |
| SCHEMBL10639964 | 0.78 | ADH1A (0.44) | ADH1AADH1CADH1BMEN1KMT2A | |
| SCHEMBL7511009 | 0.78 | MEN1 (0.38) | ADH1AADH1CADH1BMEN1KMT2A | |
| SCHEMBL24391652 | 0.77 | ADH1A (0.42) | ADH1AADH1CADH1BMEN1KMT2A | |
| SCHEMBL24429231 | 0.74 | ADH1B (0.39) | ADH1AADH1CADH1B | |
| SCHEMBL24391650 | 0.74 | ADH1B (0.39) | ADH1AADH1CADH1B | |
| SCHEMBL7765492 | 0.73 | ADH1A (0.41) | ADH1AADH1CADH1BMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| CN-1681763-A | Chemical compounds | ASTRAZENECA AB (SE) | 2005-10-12 | — | — | CN | disclosed |
| EP-1549600-A1 | KETONES | AstraZeneca AB (SE) | 2005-07-06 | — | — | EP | disclosed |
| WO-2004011410-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2004-02-05 | — | — | WO | disclosed |