Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 3/20 | 0.33 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2449028 | 0.88 | SLC6A3 (0.34) | — | |
| SCHEMBL9967852 | 0.76 | GABRA1 (0.37) | RAPGEF4RAPGEF3 | |
| SCHEMBL9152278 | 0.72 | PDE2A (0.38) | RAPGEF4RAPGEF3 | |
| SCHEMBL2460935 | 0.72 | MEN1 (0.38) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31410065 | 0.71 | PDE2A (0.36) | RAPGEF4 | |
| SCHEMBL1331197 | 0.69 | CHRM3 (0.30) | — | |
| SCHEMBL7934061 | 0.69 | RAPGEF4 (0.42) | RAPGEF4 | |
| SCHEMBL9152935 | 0.66 | SLC6A3 (0.41) | RAPGEF4RAPGEF3 | |
| SCHEMBL1155869 | 0.64 | — | — | |
| SCHEMBL1360451 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2367786-A1 | NOVEL 1 -ALKYL- 3 -HYDROXY- 3 -PHENYLAZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NSAB, Filial af NeuroSearch Sweden AB, Sverige (DK) | 2011-09-28 | — | — | EP | disclosed |
| WO-2010058020-A1 | NOVEL 1 -ALKYL- 3 -HYDROXY- 3 -PHENYLAZETIDINE DERIVATIVES USEFUL AS MODULATORS OF CORTICAL CATECHOLAMINERGIC NEUROTRANSMISSION | NSAB, FILIAL AF NEUROSEARCH SWEDEN AB, SVERIGE (DK) | 2010-05-27 | — | — | WO | disclosed |