SCHEMBL24569754

SCHEMBL24569754

CC1(C)c2ccccc2N2c3ccccc3C3(c4ccccc4C(=O)c4ccccc43)c3cccc1c32

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 8/20 0.39
KMT2A Q03164 3/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.35
HTT P42858 2/20 0.35
NPC1 O15118 1/20 0.35
USP2 O75604 1/20 0.35
POLB P06746 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 1/20 0.33
LMNA P02545 1/20 0.33
PLIN1 O60240 1/20 0.33
ALDH1A1 P00352 1/20 0.33
PLIN5 Q00G26 1/20 0.33
ABHD5 Q8WTS1 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
GRK6 P43250 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24608664 0.91 KMT2A (0.37) PGRKMT2AMEN1MAPTNPC1
SCHEMBL24608648 0.90 PGR (0.37) PGRKMT2AMEN1MAPTHTT
SCHEMBL24569265 0.88 TYMS (0.35) PGRKMT2AMEN1MAPTHTT
SCHEMBL24569838 0.88 TYMS (0.35) PGRKMT2AMEN1MAPTHTT
SCHEMBL24608704 0.87 ALDH1A1 (0.40) PGRKMT2AMEN1MAPTNPC1
SCHEMBL24608646 0.87 ALDH1A1 (0.43) PGRKMT2AMEN1MAPTALDH1A1
SCHEMBL24608745 0.87 ELANE (0.38) PGRKMT2AMEN1MAPTRAB9A
SCHEMBL24608660 0.87 PGR (0.35) PGRKMT2AMEN1MAPTHTT
SCHEMBL22969897 0.85 PGR (0.44) PGRKMT2AMEN1MAPTHTT
SCHEMBL24608741 0.84 PDK2 (0.36) PGRKMT2AMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11917912-B2 Organic compound, organic light-emitting element, display apparatus, photoelectric conversion apparatus, electronic apparatus, illumination apparatus, moving object, and exposure light source CANON KABUSHIKI KAISHA (JP) 2024-02-27 US disclosed
US-11917912-B2 Organic compound, organic light-emitting element, display apparatus, photoelectric conversion apparatus, electronic apparatus, illumination apparatus, moving object, and exposure light source CANON KABUSHIKI KAISHA (JP) 2024-02-27 US disclosed
US-20220216423-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2022-07-07 US disclosed
EP-4019504-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE CANON KABUSHIKI KAISHA (JP) 2022-06-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11917912-B2 Organic compound, organic light-emitting element, display apparatus, photoelectric conversion apparatus, electronic apparatus, illumination apparatus, moving object, and exposure light source AOX1, SOD1, L1CAM PGR 3047/4885KMT2A 2215/4885MEN1 2311/4885
US-20220216423-A1 ORGANIC COMPOUND, ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY APPARATUS, PHOTOELECTRIC CONVERSION APPARATUS, ELECTRONIC APPARATUS, ILLUMINATION APPARATUS, MOVING OBJECT, AND EXPOSURE LIGHT SOURCE AOX1, SOD1, L1CAM PGR 3047/4885KMT2A 2215/4885MEN1 2311/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.