SCHEMBL245744

SCHEMBL245744

Cc1ccc2c(c1)CC(C)(CO)C2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 1/20 0.36
METAP1 P53582 1/20 0.33
ALDH1A1 P00352 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 1/20 0.33
ALOX12 P18054 1/20 0.33
TRPM5 Q9NZQ8 2/20 0.32
CYP3A4 P08684 2/20 0.32
HTR5A P47898 1/20 0.32
AVPR1A P37288 4/20 0.32
DPP8 Q6V1X1 2/20 0.31
DPP9 Q86TI2 2/20 0.31
TP53 P04637 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
F2 P00734 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28207585 1.00 ADRA2A (0.36) ADRA2AMETAP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL29364253 1.00 ADRA2A (0.36) ADRA2AMETAP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL28207065 1.00 ADRA2A (0.36) ADRA2AMETAP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL31012300 0.86 ADRA2A (0.39) ADRA2AALDH1A1LMNACYP3A4HTT
SCHEMBL30441385 0.86 ADRA2A (0.39) ADRA2AALDH1A1LMNACYP3A4HTT
SCHEMBL20165806 0.86 ADRA2A (0.39) ADRA2AALDH1A1LMNACYP3A4HTT
SCHEMBL20165771 0.86 ADRA2A (0.46) ADRA2AALDH1A1CYP3A4DRD2DRD1
SCHEMBL11532437 0.82 LMNA (0.38) ADRA2AMETAP1ALDH1A1SMN1; SMN2LMNA
SCHEMBL20584781 0.81 ADRA2A (0.35) ADRA2AMETAP1TRPM5HTR5ADPP8
SCHEMBL30834260 0.81 ADRA2A (0.35) ADRA2AMETAP1TRPM5HTR5ADPP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 591 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE50800-E1 Pro-fragrance compounds FIRMENICH SA (CH) 2026-02-17 US claimed
US-12509482-B2 3′-ketoglycoside compound for the slow release of a volatile alcohol GLYCOSCIENCE, S.L. (ES) 2025-12-30 US claimed
US-20250186646-A1 Use of Volatile Compositions to Limit or Eliminate Perception of Fecal Malodour FIRMENICH SA (CH) 2025-06-12 US claimed
US-20250134790-A1 ANTIMICROBIAL COMPOSITIONS FIRMENICH SA (CH) 2025-05-01 US claimed
EP-4519404-A1 METHODS FOR ENHANCING MENTAL PERFORMANCE AND COMPOSITIONS FOR USE THEREIN Firmenich SA (CH) 2025-03-12 EP claimed
EP-4514477-A1 FRAGRANCE COMPOSITIONS HAVING LONG-LASTING TRAIL PERFORMANCE Firmenich SA (CH) 2025-03-05 EP claimed
US-20250009924-A1 Indane Derivatives for Malodor Counteraction FIRMENICH SA (CH) 2025-01-09 US claimed
EP-4218837-B1 VOLATILE COMPOSITIONS TO LIMIT OR ELIMINATE PERCEPTION OF FECAL MALODOUR FIRMENICH & CIE (CH) 2024-11-27 EP claimed
US-20240238177-A1 USE OF VOLATILE COMPOUNDS TO MODULATE THE PERCEPTION OF FLORAL MUGUET FIRMENICH SA (CH) 2024-07-18 US claimed
WO-2024133645-A1 ANTI-DANDRUFF COMPOSITIONS FIRMENICH SA (CH) 2024-06-27 WO claimed
EP-2760983-B1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL FIRMENICH & CIE (CH) 2015-06-17 EP claimed
WO-2014202416-A1 COMPOUNDS FOR A CONTROLLED RELEASE OF ACTIVE MOLECULES FIRMENICH SA (CH) 2014-12-24 WO claimed
US-20140234244-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL® FIRMENICH SA (CH) 2014-08-21 US claimed
EP-2760983-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL Firmenich SA (CH) 2014-08-06 EP claimed
EP-2694633-A1 FORMULATIONS WITH A LONG-LASTING FLORAL FRAGRANCE EXCLUDING 4-(4-HYDROXY-4- METHYLPENTYL)-3-CYCLOHEXENECARBOXALDEHYDE Beiersdorf AG (DE) 2014-02-12 EP claimed
WO-2013045301-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL® FIRMENICH SA (CH) 2013-04-04 WO claimed
WO-2012136651-A1 FORMULATIONS WITH A LONG-LASTING FLORAL FRAGRANCE EXCLUDING 4-(4-HYDROXY-4- METHYLPENTYL)-3-CYCLOHEXENECARBOXALDEHYDE BEIERSDORF AG (DE) 2012-10-11 WO claimed
EP-1022265-B1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH & CIE (CH) 2003-03-26 EP claimed
US-6323173-B1 COMPOUNDS WHICH DEVELOP FRESH, HUMIC, VERY PLEASANT FRAGRANCE OF LILY OF THE VALLEY TYPE; GOOD STABILITY AND EXCELLENT TENACITY FIRMENICH SA (CH) 2001-11-27 US claimed
EP-1022265-A1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH SA (CH) 2000-07-26 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250009924-A1 Indane Derivatives for Malodor Counteraction MAL2, MTNR1A, LPO ADRA2A 94/4885METAP1 779/4885ALDH1A1 150/4885
US-12509482-B2 3′-ketoglycoside compound for the slow release of a volatile alcohol EBP, MGAT1, MGAT3 ADRA2A 402/4885METAP1 2823/4885ALDH1A1 952/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.